Recombinant Anti-CCR3 Vesicular Antibody, EV Displayed (VS-0425-YC731) (CAT#: VS-0425-YC731)
The Recombinant Anti-CCR3 Vesicular Antibody, EV Displayed (VS-0425-YC731) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CCR3-expressed cells or tissues. CCR3 is a protein associated with chemokine receptor activity, linked to diseases like Folliculotropic Mycosis Fungoides. It participates in pathways like Akt signaling with CCR1 as a paralog.

(Immunofluorescent staining of human cell line RT4 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69514/1943_C10_3_selected.jpg

(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_B_6_1.jpg

(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_7_4.jpg

(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_7_5.jpg

(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_4_6.jpg

(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_9_8.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000183625-CCR3
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CCR3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-C motif chemokine receptor 3
- Biological Process
- Host-virus interaction
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Plasma membrane
- Introduction
- CCR3 (C-C Motif Chemokine Receptor 3) is a Protein Coding gene. Diseases associated with CCR3 include Folliculotropic Mycosis Fungoides and Aids Dementia Complex. Among its related pathways are Akt Signaling and IL1 and megakaryocytes in obesity. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CCR1.
- Alternative Names
- CC-CKR-3, CD193, CKR3, CMKBR3
- Gene ID
- 1232
- UniProt ID
- P51677
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CCR3"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1624z | Mouse Anti-CCR3 Recombinant Antibody (clone 27C5) | WB, ELISA, FC | Mouse IgG1 |
MOB-0369CT | Mouse Anti-CCR3 Recombinant Antibody (clone 6F9) | FC, IF, IHC-Fr | Mouse IgG2a |
FAMAB-0308-CN | Mouse Anti-CCR3 Recombinant Antibody (clone 7B11) | FC, IF, WB | Mouse IgG |
FAMAB-1029CQ | Mouse Anti-CCR3 Recombinant Antibody (clone 5E8-G9-B4) | FC | Mouse IgG2b |
VS3-FY2111 | Rabbit Anti-CCR3 Recombinant Antibody (clone R82-6D-6) | WB, IHC-P, IF | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0425-YC731. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application:
Application: ELISA, SPR, Inhib, FuncS
Application: IHC, ELISA, FC, WB, ADCC, FuncS
Application: WB, ELISA
Application: ELISA, WB, Neut, Funcs, IHC, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: WB, ELISA, FC, IHC, IF, IP
Application: Neut, IHC, Activ, FuncS, IF, ELISA
Application: Inhib, FC, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.