Mouse Anti-CCR3 Recombinant Antibody (clone 7B11); scFv Fragment

CAT#: FAMAB-0308-CN-S(P)

The antibody 7B11 is specific for CCR3 and has the properties of a true receptor antagonist. 7B11 blockes binding of various radiolabeled chemokines to either CCR3 transfectants, or eosinophils. Pretreatment of eosinophils with this mAb blockes chemotaxis and calcium flux induced by all CCR3 ligands.

Gene Expression
Figure 1 IF staining of human cell line RT4 Figure 2 Esophagus Figure 3 Liver Figure 4 Kidney Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Cell line enriched (RPMI-8226)

Specifications

  • Immunogen
  • L1.2 transfectants expressing high levels of CCR3
  • Host Species
  • Mouse
  • Type
  • Mouse scFv
  • Specificity
  • Human CCR3
  • Species Reactivity
  • Human
  • Clone
  • 7B11

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Chemokine (C-C Motif) Receptor 3; Eosinophil Eotaxin Receptor; C-C CKR-3; CC-CKR-3; CMKBR3; CCR-3; CKR3; Eosinophil CC Chemokine Receptor 3; CC Chemokine Receptor 3; B-Chemokine Receptor; CD193 Antigen; CD193
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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