Recombinant Anti-CD1D Vesicular Antibody, EV Displayed (VS-0425-YC231)
CAT#: VS-0425-YC231
The Recombinant Anti-CD1D Vesicular Antibody, EV Displayed (VS-0425-YC231) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD1D-expressed cells or tissues. The CD1D is a molecule involved in immune response pathways, related to diseases like Autoimmune Disease. It engages in receptor and cell adhesion molecule binding.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1466_F8_4_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1576_B7_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1521_F8_2_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_9_8.jpg
Normal Tissue
Figure 8 Spleen
Cells in white pulp
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_B_8_4.jpg
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD1D
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD1d molecule
- Biological Process
- Immunity, Innate immunity
- Cellular Localization
- Endoplasmic reticulum
- Introduction
- CD1D (CD1d Molecule) is a Protein Coding gene. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include receptor activity and cell adhesion molecule binding. An important paralog of this gene is CD1E.
- Gene ID
- 102142140
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| MOB-1922z | Mouse Anti-CD1D Recombinant Antibody (clone 16G11) | WB, ELISA, IHC | Mouse IgG1 |
| MOB-1733MZ | Mouse Anti-CD1D Recombinant Antibody (clone 62.2) | FC | Mouse IgG2b |
| HPAB-0088-LS | Human Anti-CD1D Recombinant Antibody (clone 402.8) | Inhib, ELISA | Humanized IgG |
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| CAT | Product Name | Application | Type |
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| TAB-1629CL | Anti-Human CD1D Recombinant Antibody (401.11) | ELISA, Inhib | Human antibody |
| TAB-1629CL-S(P) | Anti-Human CD1D Recombinant Antibody scFv Fragment (401.11) | ELISA, Inhib | Human antibody |
| TAB-1630CL-S(P) | Anti-Human CD1D Recombinant Antibody scFv Fragment (402.8) | ELISA, FC, Inhib | Human antibody |
| TAB-1629CL-F(E) | Anti-Human CD1D Recombinant Antibody Fab Fragment (401.11) | ELISA, Inhib | Human antibody |
| TAB-1630CL-F(E) | Anti-Human CD1D Recombinant Antibody Fab Fragment (402.8) | ELISA, FC, Inhib | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-290CQ | Mouse Anti-CD1D Recombinant Antibody (clone 51.1) | FC, IHC, IP, Stim, WB, Block | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0088-LS-S(P) | Human Anti-CD1D Recombinant Antibody (clone 402.8); scFv Fragment | Inhib, ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0088-LS-F(E) | Human Anti-CD1D Recombinant Antibody (clone 402.8); Fab Fragment | Inhib, ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF788 | PE-Human CD1d Tetramer - Negative Control | FCM | |
| MHC-YF789 | PE-Human CD1d Tetramer - Empty | FCM | |
| MHC-YF791 | APC-Human CD1d Tetramer - Negative Control | FCM | |
| MHC-YF792 | APC-Human CD1d Tetramer - Empty | FCM | |
| MHC-YF794 | PE-Mouse CD1d Tetramer - Negative Control | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1133 | Anti-Mouse CD1D Immunohistochemistry Kit | IHC |
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