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    Human Anti-CD1D Recombinant Antibody (clone 402.8) (CAT#: HPAB-0088-LS)

    The antibody binds CD1D and inhibits CD1D-mediated biological functions such as activation of the CD1D-restricted T cell, natural killer T (NKT) cells.

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line HEK 293
    Figure 1 IF staining of human cell line HEK 293
    (Immunofluorescent staining of human cell line HEK 293 shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1466_F8_4_selected.jpg
    Figure 2 IF staining of human cell line HaCaT
    Figure 2 IF staining of human cell line HaCaT
    (Immunofluorescent staining of human cell line HaCaT shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1576_B7_1_blue_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1521_F8_2_blue_red_green.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Neuronal cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_B_7_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Mucosal lymphoid cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_7_3.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_6_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Non-germinal center cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_9_8.jpg
    Figure 8 Spleen
    Figure 8 Spleen
    (Cells in white pulp
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_B_8_4.jpg

    Specifications

    • Immunogen
    • CD1D
    • Host Species
    • Human
    • Derivation
    • Phage display
    • Type
    • Humanized IgG
    • Specificity
    • Human CD1D
    • Species Reactivity
    • Human, Cynomolgus monkey
    • Clone
    • 402.8
    • Applications
    • Inhib, ELISA
    • Related Disease
    • Psoriasis, ulcerative colitis, primary biliary cirrhosis, atherosclerosis

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • R3; CD1A; R3G1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone 402.8"

    See other products for "CD1d"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Single Domain Antibodies IgG Antibodies Human Antibodies Blocking Antibodies ScFv Antibodies Fab Antibodies CD1d Tetramers Extracellular Vesicle Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    NAB-418-VHH Recombinant Anti-Human CD1d VHH Single Domain Antibody IP, FC, ChiP, Neut Llama VHH

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