Human Anti-CD1D Recombinant Antibody (clone 402.8); Fab Fragment
CAT#: HPAB-0088-LS-F(E)
The antibody binds CD1D and inhibits CD1D-mediated biological functions such as activation of the CD1D-restricted T cell, natural killer T (NKT) cells.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1466_F8_4_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1576_B7_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72662/1521_F8_2_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_A_9_8.jpg
Normal Tissue
Figure 8 Spleen
Cells in white pulp
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16107/35972_B_8_4.jpg
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Specifications
- Immunogen
- CD1D
- Host Species
- Human
- Derivation
- Phage display
- Type
- Humanized Fab
- Specificity
- Human CD1D
- Species Reactivity
- Human, Cynomolgus monkey
- Clone
- 402.8
- Applications
- Inhib, ELISA
- Related Disease
- Psoriasis, ulcerative colitis, primary biliary cirrhosis, atherosclerosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 402.8"
- CAT
- Product Name
See other products for "CD1d"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-418-VHH | Recombinant Anti-Human CD1d VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1922z | Mouse Anti-CD1D Recombinant Antibody (clone 16G11) | WB, ELISA, IHC | Mouse IgG1 |
| MOB-1733MZ | Mouse Anti-CD1D Recombinant Antibody (clone 62.2) | FC | Mouse IgG2b |
| HPAB-0088-LS | Human Anti-CD1D Recombinant Antibody (clone 402.8) | Inhib, ELISA | Humanized IgG |
| VS7-HM448 | Mouse Anti-CD1D Recombinant Antibody (clone 3A6G3) | FCM | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1629CL | Anti-Human CD1D Recombinant Antibody (401.11) | ELISA, Inhib | Human antibody |
| TAB-1629CL-S(P) | Anti-Human CD1D Recombinant Antibody scFv Fragment (401.11) | ELISA, Inhib | Human antibody |
| TAB-1630CL-S(P) | Anti-Human CD1D Recombinant Antibody scFv Fragment (402.8) | ELISA, FC, Inhib | Human antibody |
| TAB-1629CL-F(E) | Anti-Human CD1D Recombinant Antibody Fab Fragment (401.11) | ELISA, Inhib | Human antibody |
| TAB-1630CL-F(E) | Anti-Human CD1D Recombinant Antibody Fab Fragment (402.8) | ELISA, FC, Inhib | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-290CQ | Mouse Anti-CD1D Recombinant Antibody (clone 51.1) | FC, IHC, IP, Stim, WB, Block | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0088-LS-S(P) | Human Anti-CD1D Recombinant Antibody (clone 402.8); scFv Fragment | Inhib, ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF788 | PE-Human CD1d Tetramer - Negative Control | FCM | |
| MHC-YF789 | PE-Human CD1d Tetramer - Empty | FCM | |
| MHC-YF791 | APC-Human CD1d Tetramer - Negative Control | FCM | |
| MHC-YF792 | APC-Human CD1d Tetramer - Empty | FCM | |
| MHC-YF794 | PE-Mouse CD1d Tetramer - Negative Control | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC231 | Recombinant Anti-CD1D Vesicular Antibody, EV Displayed (VS-0425-YC231) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1133 | Anti-Mouse CD1D Immunohistochemistry Kit | IHC |
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