Anti-Human CD1D Recombinant Antibody (402.8) (CAT#: TAB-1630CL)
This antibody fragment which binds to CD1d can be used in treatment of conditions involving NKT (natural killer T) cell effector function.
Specific Inquiry
Inhib
Figure 1 Graphical Representation of results of assay demonstrating inhibition of tetramer binding by anti-CDld antibodies.
Inhib
Figure 2 Graphical Representation of results of assay demonstrating inhibition of IL-2 release by anti-CDld antibodies.
FC
Figure 3 Graphical Representation of results of assay demonstrating binding of anti-CDld antibodies to Primary peripheral blood mononuclear cells (PBMCs) by flow cytometry.
ELISA
Figure 4 Graphical representation of results of a competition ELISA demonstrating that highly potent anti-CDld antibodies share a similar neutralizing epitope that is different to the epitope seen by lower-potency prior-art antibodies.
Specifications
- Immunogen
- Recombinant CDld/p2M antigen
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Cynomolgus CD1d
- Clone
- 402.8
- Applications
- ELISA, FC, Inhib
- Related Disease
- Inflammatory diseases such as severe corticosteroid refractory asthma
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Inhibition.
Target
- Alternative Names
- CD1D; CD1d molecule; R3; CD1A; antigen-presenting glycoprotein CD1d; R3G1; thymocyte antigen CD1D; CD1D antigen, d polypeptide; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D
- Gene ID
- 912
- UniProt ID
- P15813
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
Recombinant Antibody
Human Antibody
Blocking Antibody
scFv Fragment Antibody
Fab Fragment Antibody
CD1d Tetramer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-418-VHH | Recombinant Anti-Human CD1d VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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