Anti-Human CD1D Recombinant Antibody (402.8) (CAT#: TAB-1630CL)

This antibody fragment which binds to CD1d can be used in treatment of conditions involving NKT (natural killer T) cell effector function.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Inhib

Figure 1 Graphical Representation of results of assay demonstrating inhibition of tetramer binding by anti-CDld antibodies.

Figure 1 Graphical Representation of results of assay demonstrating inhibition of tetramer binding by anti-CDld antibodies.

Inhib

Figure 2 Graphical Representation of results of assay demonstrating inhibition of IL-2 release by anti-CDld antibodies.

Figure 2 Graphical Representation of results of assay demonstrating inhibition of IL-2 release by anti-CDld antibodies.

FC

Figure 3 Graphical Representation of results of assay demonstrating binding of anti-CDld antibodies to Primary peripheral blood mononuclear cells (PBMCs) by flow cytometry.

Figure 3 Graphical Representation of results of assay demonstrating binding of anti-CDld antibodies to Primary peripheral blood mononuclear cells (PBMCs) by flow cytometry.

ELISA

Figure 4 Graphical representation of results of a competition ELISA demonstrating that highly potent anti-CDld antibodies share a similar neutralizing epitope that is different to the epitope seen by lower-potency prior-art antibodies.

Figure 4 Graphical representation of results of a competition ELISA demonstrating that highly potent anti-CDld antibodies share a similar neutralizing epitope that is different to the epitope seen by lower-potency prior-art antibodies.


Specifications

  • Immunogen
  • Recombinant CDld/p2M antigen
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Species Reactivity
  • Cynomolgus CD1d
  • Clone
  • 402.8
  • Applications
  • ELISA, FC, Inhib
  • Related Disease
  • Inflammatory diseases such as severe corticosteroid refractory asthma

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Inhibition.

Target

  • Alternative Names
  • CD1D; CD1d molecule; R3; CD1A; antigen-presenting glycoprotein CD1d; R3G1; thymocyte antigen CD1D; CD1D antigen, d polypeptide; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 402.8"

See other products for "CD1d"

Single-domain Antibody

CAT Product Name Application Type
NAB-418-VHH Recombinant Anti-Human CD1d VHH Single Domain Antibody IP, FC, ChiP, Neut Llama VHH

Recombinant Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-290CQ Mouse Anti-CD1D Recombinant Antibody (clone 51.1) FC, IHC, IP, Stim, WB, Block Mouse IgG2b, κ

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0088-LS-S(P) Human Anti-CD1D Recombinant Antibody (clone 402.8); scFv Fragment Inhib, ELISA Humanized scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0088-LS-F(E) Human Anti-CD1D Recombinant Antibody (clone 402.8); Fab Fragment Inhib, ELISA Humanized Fab

Submit a review or a question
There are currently no Customer reviews or questions for TAB-1630CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare