Recombinant Anti-CD200R1 Vesicular Antibody, EV Displayed (VS-0425-YC667)

CAT#: VS-0425-YC667

The Recombinant Anti-CD200R1 Vesicular Antibody, EV Displayed (VS-0425-YC667) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD200R1-expressed cells or tissues. CD200R1 is a receptor that suppresses immune response, associated with pathways like antigen processing and presentation, with CD200R1L as a paralog.

Gene Expression
Figure 1 IF staining of human cell line HEL Figure 2 RNA cell line category: Cell line enriched (HEL)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CD200R1
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CD200 receptor 1
  • Biological Process
  • Host-virus interaction
  • Molecular Function
  • Receptor
  • Cellular Localization
  • Plasma membrane
  • Introduction
  • CD200R1 (CD200 Receptor 1) is a Protein Coding gene. Diseases associated with CD200R1 include Primary Hypertrophic Osteoarthropathy. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is CD200R1L.
  • Alternative Names
  • CD200R, HCRTR2, MOX2R, OX2R
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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