Recombinant Anti-CD48 Vesicular Antibody, EV Displayed (VS-0425-YC685)
CAT#: VS-0425-YC685
The Recombinant Anti-CD48 Vesicular Antibody, EV Displayed (VS-0425-YC685) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD48-expressed cells or tissues. CD48 enables receptor ligand activity, participating in mast cell activation, and is part of a protein complex with a human ortholog.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli fibrillar center, plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55146/1674_C10_33_selected.jpg
Normal Tissue
Figure 2 High expression in tonsil.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2497/ihc_selected.jpg
Normal Tissue
Figure 3 Low expression in cerebral cortex.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2497/6580_B_7_5_val_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2497/6580_A_9_8.jpg
Normal Tissue
Figure 5 Tonsil
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2497/6580_A_4_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Daudi, HMC-1, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117091-CD48
❮
❯
Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD48
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD48 molecule
- Cellular Localization
- Plasma membrane, Nucleoli fibrillar center, Cytosol
- Introduction
- Predicted to enable receptor ligand activity. Involved in mast cell activation. Part of protein-containing complex. Orthologous to human CD48 (CD48 molecule).
- Alternative Names
- SLAMF2
- Gene ID
- 245962
- UniProt ID
- P10252
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
| MOB-1537z | Mouse Anti-CD48 Recombinant Antibody (clone 12H3) | FC, FuncS | Mouse IgG1 |
| VS3-XY357 | Mouse Anti-CD48 Recombinant Antibody, FITC (clone 4A156-4H9) | FC, IF | Mouse IgG1 |
| VS3-XY358 | Mouse Anti-CD48 Recombinant Antibody, PE (clone 4A156-4H9) | FC, IF | Mouse IgG1 |
| VS3-XY359 | Mouse Anti-CD48 Recombinant Antibody (clone 4A156-4H9) | FC, IF | Mouse IgG1 |
| VS13-YC168 | Rabbit Anti-CD48 Recombinant Antibody (VS13-YC168) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-132CL | Anti-Human CD48 Recombinant Antibody | ELISA, Inhib, FuncS | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-304LC | Human Anti-CD48 Recombinant Antibody (TAB-304LC) | ELISA, FuncS | Human IgG4 |
| TAB-305LC | Mouse Anti-CD48 Recombinant Antibody (TAB-305LC) | ELISA | Mouse IgG |
| TAB-306LC | Human Anti-CD48 Recombinant Antibody (TAB-306LC) | ELISA | Human IgG |
| TAB-304LC-F(E) | Human Anti-CD48 Recombinant Antibody (TAB-304LC-F(E)); Fab Fragment | ELISA | Human Fab |
| TAB-305LC-F(E) | Mouse Anti-CD48 Recombinant Antibody (TAB-305LC-F(E)); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-307LC | Mouse Anti-CD48 Recombinant Antibody (TAB-307LC) | ELISA, Cyt, CDC | Mouse IgG2a |
| TAB-307LC-S(P) | Mouse Anti-CD48 Recombinant Antibody; scFv Fragment (TAB-307LC-S(P)) | ELISA | Mouse scFv |
| TAB-307LC-F(E) | Mouse Anti-CD48 Recombinant Antibody; Fab Fragment (TAB-307LC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-390CQ | Hamster Anti-CD48 Recombinant Antibody (clone HM48-1) | FC, IP, Costim, Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0566 | Hi-Affi™ Rabbit Anti-CD48 Recombinant Antibody (clone DS566AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1325LY-S(P) | Human Anti-CD48 Recombinant Antibody; scFv Fragment (HPAB-1325LY-S(P)) | ELISA | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1325LY-F(E) | Human Anti-CD48 Recombinant Antibody; Fab Fragment (HPAB-1325LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1298 | AbPlus™ Anti-Cd48 Magnetic Beads (VS-0724-YC1298) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC119 | Mouse Anti-CD48 Recombinant Antibody Hexamer (VS-0924-YC119), CDC Enhanced | ELISA, Cyt, CDC | Antibody hexamer |
| VS-0924-YC120 | Mouse Anti-CD48 Recombinant Antibody Hexamer (VS-0924-YC120), CDC Enhanced | ELISA, Inhib, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY100 | Mouse Anti-NHP CD48 Recombinant Antibody (clone MEM-102) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY57 | CytoStream™ Armenian Hamster Anti-CD48 Recombinant Antibody (clone HM48-1) | FC, Block, Funcs, IP, WB | Armenian Hamster IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1193 | Anti-CD48 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1194 | Anti-Human CD48 Immunohistochemistry Kit | IHC |
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