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CD48

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Anti-CD48 Products

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For Research Use Only. Not For Clinical Use.


Background

This is an antibody directed against the CD48 antigen has a strong anti-tumour effect in an animal model. The anti-tumour effect has been demonstrated in an animal model where treatment of mice containing tumour cells with an anti-CD48 antibody gave long term survival (cures) over those treated with a control antibody.
Protein class

CD markers, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (NK-cells, T-cells, monocytes, B-cells, dendritic cells, Kupffer cells, Macrophages)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Daudi, HMC-1, U-266/70, U-266/84)

Interaction

Interacts with CD2. Interacts with CD244 (PubMed:9841922, PubMed:27249817). Interacts with LCK (PubMed:12007789).

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