Recombinant Anti-CDH17 Vesicular Antibody, EV Displayed (VS-0425-YC250) (CAT#: VS-0425-YC250)
The Recombinant Anti-CDH17 Vesicular Antibody, EV Displayed (VS-0425-YC250) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH17-expressed cells or tissues. The CDH17 is Cadherin 17, associated with gastric cancer, involved in signaling pathways.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/1030_A11_3_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/1030_A11_3_selected.jpg
Figure 2 Duodenum
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23614/52777_A_9_2_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23614/52777_A_9_2_val_selected.jpg
Figure 3 Small intestine
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75% Paneth cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_6_2.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75% Paneth cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_6_2.jpg
Figure 4 Colon
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_9_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, OE19, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079112-CDH17
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079112-CDH17
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDH17
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cadherin 17
- Biological Process
- Cell adhesion, Transport
- Cellular Localization
- Cell Junctions, Nucleoplasm
- Introduction
- CDH17 (Cadherin 17) is a Protein Coding gene. Diseases associated with CDH17 include Gastric Cancer and Gastric Adenocarcinoma. Among its related pathways are ERK Signaling and Gastric cancer. Gene Ontology (GO) annotations related to this gene include calcium ion binding and proton-dependent oligopeptide secondary active transmembrane transporter activity. An important paralog of this gene is CDH16.
- Alternative Names
- cadherin, HPT-1
- Gene ID
- 1015
- UniProt ID
- Q12864
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2803z | Mouse Anti-CDH17 Recombinant Antibody (clone 23F8) | WB, ELISA, IHC | Mouse IgG1 |
| HPAB-M0033-YC | Mouse Anti-CDH17 Recombinant Antibody (HPAB-M0033-YC) | ELISA, FC, FuncS, IHC | Mouse IgG |
| HPAB-M0034-YC | Mouse Anti-CDH17 Recombinant Antibody (HPAB-M0034-YC) | ELISA, FC, FuncS, IHC | Mouse IgG |
| HPAB-M0035-YC | Human Anti-CDH17 Recombinant Antibody (HPAB-M0035-YC) | ELISA, FC, FuncS, IHC | Humanized IgG |
| VS-0524-YC24 | Human Anti-CDH17 Recombinant Antibody (clone AV17.3) | ELISA, IF | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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