Human Anti-CDH17 Recombinant Antibody (clone D2005) (CAT#: HPAB-2063LY)
This product is a chimeric (mouse/human) antibody that recognizes CDH17.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Figure 1 Competition assay of the hybridoma culture supernatant.
All of the data shown are the means-standard deviations of triplicate assays.
Kusano-Arai, O., Iwanari, H., Kudo, S., Kikuchi, C., Yui, A., Akiba, H.,... & Hamakubo, T. (2018). Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 1-11.
FC
Figure 2 Specific binding to the cell surface CDH17 was demonstrated by flow cytometry.
The filled histograms indicate anti-CDH17 mAbs, and the open histograms indicate control IgG binding to AGS cells (upper panels) and MKN74 cells (lower panels). The numbers at the top designate the clone number of the anti-CDH17 mAbs. CDH17, Cadherin-17; mAb, monoclonal antibody.
Kusano-Arai, O., Iwanari, H., Kudo, S., Kikuchi, C., Yui, A., Akiba, H.,... & Hamakubo, T. (2018). Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 1-11.
ELISA
Figure 3 Dose-dependent binding of the anti-CDH17 mAbs.
All of the data shown are the means-standard deviations of triplicate assay.
Kusano-Arai, O., Iwanari, H., Kudo, S., Kikuchi, C., Yui, A., Akiba, H.,... & Hamakubo, T. (2018). Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 1-11.
Specifications
- Host Species
- Human
- Type
- Chimeric (Mouse/Human) IgG
- Specificity
- Human CDH17
- Species Reactivity
- Human
- Clone
- D2005
- Applications
- ELISA
- Conjugate
- None, customized conjugetion is available
Product Property
- Purification
- Protein A/G purified
- Purity
- >95% determined by SDS-PAGE (Reduced conditions), customized purity is available
- Format
- Liquid or lyophilized powder
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- HPT1; CDH16; HPT-1; cadherin-17; HPT-1 cadherin; LI cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; liver-intestine cadherin
- Gene ID
- 1015
- UniProt ID
- Q12864
- Protein Refseq
- NP_001138135.1
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1415CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1415CL-F(E)) | ELISA | Mouse Fab |
| TAB-1416CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1416CL-F(E)) | ELISA | Mouse Fab |
| TAB-1417CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1417CL-F(E)) | ELISA | Mouse Fab |
| TAB-1418CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1418CL-F(E)) | ELISA | Mouse Fab |
| TAB-1419CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1419CL-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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