Recombinant Rabbit Anti-CDKN2A Antibody (clone R02-6H1) (CAT#: VS3-FY360)
This product is a recombinant rabbit antibody that recognizes human and mouse CDKN2A protein. It can detect a band of approximately 17 kDa (observedd molecular weight: 17 kDa).
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WB
Figure 1. Recombinant Rabbit Anti-CDKN2A Antibody (clone R02-6H1) in WB.
Western blot analysis of CDKN2A/p16INK4a in 3T3, HeLa lysates using CDKN2A antibody.
Specifications
- Immunogen
- Recombinant protein of human CDKN2A/p16INK4a
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse CDKN2A
- Species Reactivity
- Human, Mouse
- Clone
- R02-6H1
- Applications
- Western Blot, Immunoprecipitation
- Conjugate
- Unconjugated
- MW
- Calculated MW: 17 kDa; Observed MW: 17 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Cyclin Dependent Kinase Inhibitor 2A; Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4); Cyclin-Dependent Kinase 4 Inhibitor A; Cyclin-Dependent Kinase Inhibitor 2A; Multiple Tumor Suppressor 1; Alternative Reading Frame; P16-INK4A; P16INK4A; P14ARF; CDKN2; CDK4I; MTS-1; MTS1; MLM
- Gene ID
- 1029
- UniProt ID
- P42771
- Sequence Similarities
- Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylation seems to increase interaction with CDK4.
- Protein Refseq
- NP_000068.1; NP_001182061.1; NP_478104.2
- Function
- Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Recommended Products
Secondary Antibody
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0116MZ | Chicken Anti-CDKN2A Polyclonal IgY | WB | Chicken antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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