Recombinant Rabbit Anti-CDKN2A Antibody (clone R02-6H1) (CAT#: VS3-FY360)
This product is a recombinant rabbit antibody that recognizes human and mouse CDKN2A protein. It can detect a band of approximately 17 kDa (observedd molecular weight: 17 kDa).
Specific Inquiry
WB
Figure 1. Recombinant Rabbit Anti-CDKN2A Antibody (clone R02-6H1) in WB.
Western blot analysis of CDKN2A/p16INK4a in 3T3, HeLa lysates using CDKN2A antibody.
Specifications
- Immunogen
- Recombinant protein of human CDKN2A/p16INK4a
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse CDKN2A
- Species Reactivity
- Human, Mouse
- Clone
- R02-6H1
- Applications
- Western Blot, Immunoprecipitation
- Conjugate
- Unconjugated
- MW
- Calculated MW: 17 kDa; Observed MW: 17 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Cyclin Dependent Kinase Inhibitor 2A; Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4); Cyclin-Dependent Kinase 4 Inhibitor A; Cyclin-Dependent Kinase Inhibitor 2A; Multiple Tumor Suppressor 1; Alternative Reading Frame; P16-INK4A; P16INK4A; P14ARF; CDKN2; CDK4I; MTS-1; MTS1; MLM
- Gene ID
- 1029
- UniProt ID
- P42771
- Sequence Similarities
- Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylation seems to increase interaction with CDK4.
- Protein Refseq
- NP_000068.1; NP_001182061.1; NP_478104.2
- Function
- Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CDKN2A"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1779z | Mouse Anti-CDKN2A Recombinant Antibody (clone 30C1) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MRO-1141-CN | Rabbit Anti-CDKN2A Recombinant Antibody (clone CBACN-415) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-1769-CN | Rabbit Anti-CDKN2A Polyclonal Antibody (MRO-1769-CN) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0376U | Rabbit Anti-CDKN2A Recombinant Antibody (clone R19-D) | IHC-P | Rabbit IgG |
| ZG-0394U | Mouse Anti-CDKN2A Recombinant Antibody (clone R15-A) | IHC-P | Mouse IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0116MZ | Chicken Anti-CDKN2A Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0642 | Hi-Affi™ Rabbit Anti-CDKN2A Recombinant Antibody (clone DS642AB) | FC, ICC, IF, WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0877LY-S(P) | Mouse Anti-CDKN2A Recombinant Antibody (clone CBL015); scfv Fragment | IHC, WB | Mouse scfv |
| HPAB-M0037-YC-S(P) | Mouse Anti-CDKN2A Recombinant Antibody (clone P1); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0877LY-F(E) | Mouse Anti-CDKN2A Recombinant Antibody (clone CBL015); Fab Fragment | IHC, WB | Mouse Fab |
| HPAB-M0037-YC-F(E) | Mouse Anti-CDKN2A Recombinant Antibody (clone P1); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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