Recombinant Anti-HBEGF Vesicular Antibody, EV Displayed (VS-0425-YC629) (CAT#: VS-0425-YC629)
The Recombinant Anti-HBEGF Vesicular Antibody, EV Displayed (VS-0425-YC629) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to HBEGF-expressed cells or tissues. HBEGF is a heparin-binding EGF-like growth factor, involved in RET signaling and implicated in diseases like diphtheria.

(Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/ihc_selected.jpg

(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_B_8_5.jpg

(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_A_8_3.jpg

(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_A_9_5.jpg

(Cardiomyocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_B_6_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113070-HBEGF
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- HBEGF
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Heparin binding EGF like growth factor
- Molecular Function
- Growth factor, Heparin-binding, Receptor
- Cellular Localization
- Golgi apparatus, Vesicles
- Introduction
- HBEGF (Heparin Binding EGF Like Growth Factor) is a Protein Coding gene. Diseases associated with HBEGF include Diphtheria and Bladder Disease. Among its related pathways are RET signaling and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include growth factor activity and epidermal growth factor receptor binding. An important paralog of this gene is AREG.
- Alternative Names
- DTR, DTS, HEGFL
- Gene ID
- 1839
- UniProt ID
- Q99075
Related Resources
Downloads
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See other products for "HBEGF"
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1493z | Mouse Anti-HBEGF Recombinant Antibody (clone 25C6) | WB, IHC, Neut | Mouse IgG1 |
MOB-2309MZ | Recombinant Mouse Anti-Human HBEGF Antibody (clone 5H20), Biotin-Conjugated | ICC/IF, IP, WB | Mouse antibody |
HPAB-0119-YC | Mouse Anti-HBEGF Recombinant Antibody (clone 2F7) | ELISA, FC, WB, Neut | Mouse IgG |
VS3-FY656 | Recombinant Rabbit Anti-HBEGF Antibody (clone R08-9C2) | WB | Rabbit IgG |
VS-0723-WK72 | Human Anti-HBEGF Recombinant Antibody (VS-0723-WK72) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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