Recombinant Anti-HBEGF Vesicular Antibody, EV Displayed (VS-0425-YC629)
CAT#: VS-0425-YC629
The Recombinant Anti-HBEGF Vesicular Antibody, EV Displayed (VS-0425-YC629) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to HBEGF-expressed cells or tissues. HBEGF is a heparin-binding EGF-like growth factor, involved in RET signaling and implicated in diseases like diphtheria.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human heart muscle
Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_A_9_5.jpg
Normal Tissue
Figure 5 Heart muscle
Cardiomyocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53243/120132_B_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HBF TERT88, JURKAT, TIME, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113070-HBEGF
❮
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- HBEGF
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Heparin binding EGF like growth factor
- Molecular Function
- Growth factor, Heparin-binding, Receptor
- Cellular Localization
- Golgi apparatus, Vesicles
- Introduction
- HBEGF (Heparin Binding EGF Like Growth Factor) is a Protein Coding gene. Diseases associated with HBEGF include Diphtheria and Bladder Disease. Among its related pathways are RET signaling and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include growth factor activity and epidermal growth factor receptor binding. An important paralog of this gene is AREG.
- Alternative Names
- DTR, DTS, HEGFL
- Gene ID
- 1839
- UniProt ID
- Q99075
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Related Diseases
Bladder Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1493z | Mouse Anti-HBEGF Recombinant Antibody (clone 25C6) | WB, IHC, Neut | Mouse IgG1 |
| HPAB-0593-CN | Human Anti-HBEGF Recombinant Antibody (HPAB-0593-CN) | WB, ELISA, FC, Neut | Chimeric (mouse/human) IgG1 |
| VS3-FY656 | Recombinant Rabbit Anti-HBEGF Antibody (clone R08-9C2) | WB | Rabbit IgG |
| VS-0723-WK72 | Human Anti-HBEGF Recombinant Antibody (VS-0723-WK72) | FC | Chimeric (rabbit/human) IgG1 |
| VS-0624-FY12 | Human Anti-HBEGF Recombinant Antibody (clone KM3966) | Neut, ADCC, FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-340CL | Anti-Human HBEGF Recombinant Antibody (KHK2866) | FuncS | Antibody |
| TAB-015CT | Anti-Human HB-EGF Recombinant Antibody | ELISA, Inhibition, FC | Humanized antibody |
| TAB-015CT-S(P) | Anti-Human HB-EGF Recombinant Antibody scFv Fragment | ELISA, Inhibition, FC | Humanized antibody |
| TAB-015CT-F(E) | Anti-Human HB-EGF Recombinant Antibody Fab Fragment | ELISA, Inhibition, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-895CQ | Mouse Anti-HBEGF Recombinant Antibody (clone MM0324-3R44) | WB, Neut | Mouse IgG2 |
| NEUT-896CQ | Mouse Anti-HBEGF Recombinant Antibody (clone CBL069) | WB, Neut | Mouse IgG2 |
| NEUT-897CQ | Mouse Anti-HBEGF Recombinant Antibody (clone CBL271) | WB, Neut, ELISA | Mouse IgG2a |
| NEUT-898CQ | Mouse Anti-HBEGF Recombinant Antibody (clone CBL374) | Neut, WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0119-YC-S(P) | Mouse Anti-HBEGF Recombinant Antibody (clone 2F7); scFv Fragment | ELISA, FC, WB, Neut | Mouse scFv |
| HPAB-0593-CN-S(P) | Mouse Anti-HBEGF Recombinant Antibody; scFv Fragment (HPAB-0593-CN-S(P)) | WB, ELISA, FC, Neut | Mouse scFv |
| HPAB-0594-CN-S(P) | Human Anti-HBEGF Recombinant Antibody; scFv Fragment (HPAB-0594-CN-S(P)) | WB, ELISA, FC, Neut | Humanized scFv |
| HPAB-0091-LS-S(P) | Mouse Anti-HBEGF Recombinant Antibody (clone HA-20); scFv Fragment | Inhib, FC, ELISA | Mouse scFv |
| HPAB-0092-LS-S(P) | Mouse Anti-HBEGF Recombinant Antibody (clone HB-20); scFv Fragment | Inhib, FC, ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0593-CN-F(E) | Human Anti-HBEGF Recombinant Antibody; Fab Fragment (HPAB-0593-CN-F(E)) | WB, ELISA, FC, Neut | Human Fab |
| HPAB-0594-CN-F(E) | Human Anti-HBEGF Recombinant Antibody; Fab Fragment (HPAB-0594-CN-F(E)) | WB, ELISA, FC, Neut | Humanized Fab |
| HPAB-0091-LS-F(E) | Mouse Anti-HBEGF Recombinant Antibody (clone HA-20); Fab Fragment | Inhib, FC, ELISA | Mouse Fab |
| HPAB-0092-LS-F(E) | Mouse Anti-HBEGF Recombinant Antibody (clone HB-20); Fab Fragment | Inhib, FC, ELISA | Mouse Fab |
| HPAB-0094-LS-F(E) | Mouse Anti-HBEGF Recombinant Antibody (clone 8d71c81e9); Fab Fragment | ELISA, Inhib, WB, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0387-YC | Recombinant Camelid Anti-HBEGF Single Domain Antibody (HPAB-M0387-YC) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3071 | Anti-HBEGF Immunohistochemistry Kit | IHC |
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