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HBEGF

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For Research Use Only. Not For Clinical Use.


HBEGF (Heparin Binding EGF Like Growth Factor) is a Protein Coding gene. Diseases associated with HBEGF include Diphtheria and Bladder Disease. Among its related pathways are RET signaling and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include growth factor activity and epidermal growth factor receptor binding. An important paralog of this gene is AREG.
Predicted location

Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Basal prostatic cells, Urothelial cells, Squamous epithelial cells)

Immune cell specificity

Group enriched (intermediate monocyte, non-classical monocyte, myeloid DC)

Cell line specificity

Cell line enhanced (HBF TERT88, JURKAT, TIME, U-698)

Interaction

Interacts with FBLN1 (By similarity). Interacts with EGFR and ERBB4.

Molecular function

Growth factor, Heparin-binding, Receptor

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