Recombinant Anti-ITGA5 Vesicular Antibody, EV Displayed (VS-0425-YC570)
CAT#: VS-0425-YC570
The Recombinant Anti-ITGA5 Vesicular Antibody, EV Displayed (VS-0425-YC570) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGA5-expressed cells or tissues. ITGA5 is an integrin alpha chain forming a fibronectin receptor with the beta 1 subunit. High expression correlates with tumor progression in lung cancer.
Gene Expression
Normal Tissue
Figure 1 High expression in placenta
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/ihc_selected.jpg
Normal Tissue
Figure 2 Low expression in skeletal muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_B_1_6_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human placenta
Immunohistochemical staining of human placenta shows distinct cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9008/ihc_selected.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_A_8_4.jpg
Normal Tissue
Figure 5 Placenta
Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Hofbauer cells Staining: Low Intensity: Moderate Quantity: <25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_A_3_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, TIME, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000161638-ITGA5
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGA5
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit alpha 5
- Biological Process
- Cell adhesion, Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Integrin, Receptor
- Introduction
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
- Alternative Names
- CD49e, FNRA
- Gene ID
- 3678
- UniProt ID
- P08648
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC570. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ITGA5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1727z | Mouse Anti-ITGA5 Recombinant Antibody (clone 11B1) | WB, ELISA, FC, IHC | Mouse IgG2a |
| MOB-0506CT | Recombinant Mouse anti-Human ITGA5 Monoclonal antibody (DC50f) | FC | |
| VS3-CJ513 | Rabbit Anti-ITGA5 Recombinant Antibody (VS3-CJ513) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS7-0425-WR154 | Mouse Anti-ITGA5 Monoclonal Antibody (VS7-0425-WR154) | WB, IHC-P, IF, FC, ELISA | Mouse IgG |
| VS7-0425-WR155 | Mouse Anti-ITGA5 Recombinant Antibody (VS7-0425-WR155) | WB, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-077 | Anti-Human Integrin alpha 5 beta 1 Recombinant Antibody (Volociximab) | ELISA, IHC | IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1554CQ | Recombinant Mouse Anti-ITGA5 Antibody (NKI-SAM-1) | FC, IP, ELISA, BL | IgG2b, κ |
| NEUT-1555CQ | Recombinant Armenian Hamster Anti-Itga5 Antibody (HMα5-1) | FC, BL, IP | IgG |
| NEUT-1556CQ | Recombinant Rat Anti-Itga5 Antibody (5H10-27) | FC, BL, IHC-Fr, FuncS | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1874 | Hi-Affi™ Recombinant Rabbit Anti-ITGA5 Monoclonal Antibody (DS1874AB) | WB, IHC-P, ICC, IF, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-077 | Afuco™ Anti-ITGA5 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-077) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0398-WJ-S(P) | Human Anti-ITGA5 Recombinant Antibody; scFv Fragment (HPAB-0398-WJ-S(P)) | ELISA | Humanized scFv |
| HPAB-0399-WJ-S(P) | Mouse Anti-ITGA5 Recombinant Antibody; scFv Fragment (HPAB-0399-WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0398-WJ-F(E) | Human Anti-ITGA5 Recombinant Antibody; Fab Fragment (HPAB-0398-WJ-F(E)) | ELISA | Humanized Fab |
| HPAB-0399-WJ-F(E) | Mouse Anti-ITGA5 Recombinant Antibody; Fab Fragment (HPAB-0399-WJ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1485 | AbPlus™ Anti-ITGA5 Magnetic Beads (VS-0724-YC1485) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1155 | Anti-ITGA5 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3627 | Anti-Mouse ITGA5 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3629 | Anti-Human ITGA5 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3628 | Anti-Rat ITGA5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY136 | Rabbit Anti-ITGA5 scFv-Fc Chimera (VS-0425-FY136) | ELISA, Flow, ICC, IF, IHC, BLOCK | Rabbit IgG, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, ELISA, IF
-5.jpg)
Application: Neut, FC, IHC-Fr, IP, BA
Application: ELISA, IHC, FC, IP, IF, FuncS
-3.jpg)
Application: Neut
Application: Neut, IHC, Activ, FuncS, IF, ELISA
Application: ELISA, Neut, FuncS
Application: ELISA, Neut, FuncS
Application: IF, ICC, WB, IHC-P, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
