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ITGA5
Loading...Anti-ITGA5 Products
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG4
- Application: ELISA, IHC
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- Recombinant Mouse Anti-ITGA5 Antibody (NKI-SAM-1) (NEUT-1554CQ)
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- Species Reactivity: Human, Cynomolgus Macaque
- Type: IgG2b, κ
- Application: FC, IP, ELISA, BL
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- Recombinant Rat Anti-Itga5 Antibody (5H10-27) (NEUT-1556CQ)
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- Species Reactivity: Mouse
- Type: IgG2a, κ
- Application: FC, BL, IHC-Fr, FuncS
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC
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- AbPlus™ Anti-ITGA5 Magnetic Beads (VS-0724-YC1485) (VS-0724-YC1485)
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- Target: ITGA5
- Target Species: Human
- Application: IP, Protein Purification
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- Mouse Anti-ITGA5 Recombinant Antibody (clone SNAKA51) (FAMAB-1184CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: IHC, WB, IF
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- Mouse Anti-ITGA5 Antibody (clone SNAKA51), mRNA (FAMAB-1184CQ-mRNA)
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- Species Reactivity: Human
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC, ICC, FC, ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IP, IF, FuncS, FC, Neut, ELISA
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- Human Anti-ITGA5 Recombinant Antibody (HPAB-0398-WJ) (HPAB-0398-WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
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- Mouse Anti-ITGA5 Recombinant Antibody (HPAB-0399-WJ) (HPAB-0399-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, FC, IHC
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- Mouse Anti-ITGA5 Recombinant Antibody; scFv Fragment (HPAB-0399-WJ-S(P)) (HPAB-0399-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Human Anti-ITGA5 Recombinant Antibody; Fab Fragment (HPAB-0398-WJ-F(E)) (HPAB-0398-WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Mouse Anti-ITGA5 Recombinant Antibody; Fab Fragment (HPAB-0399-WJ-F(E)) (HPAB-0399-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Human Anti-ITGA5 Recombinant Antibody; scFv Fragment (HPAB-0398-WJ-S(P)) (HPAB-0398-WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P, ICC, IF, IP, FC
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- Anti-ITGA5 Immunohistochemistry Kit (VS-0325-XY1155)
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- Species Reactivity: Human
- Target: ITGA5
- Application: IHC
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- Rabbit Anti-ITGA5 scFv-Fc Chimera (VS-0425-FY136) (VS-0425-FY136)
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- Species Reactivity: Human
- Type: Rabbit IgG, scFv-Fc
- Application: ELISA, Flow, ICC, IF, IHC, BLOCK
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- Mouse Anti-ITGA5 Monoclonal Antibody (VS7-0425-WR154) (VS7-0425-WR154)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, FC, ELISA
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- Mouse Anti-ITGA5 Recombinant Antibody (VS7-0425-WR155) (VS7-0425-WR155)
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- Species Reactivity: Human, Mouse, Rat, Bovine
- Type: Mouse IgG
- Application: WB, FC
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- Species Reactivity: Human
- Target: ITGA5
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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- Anti-Mouse ITGA5 Immunohistochemistry Kit (VS-0525-XY3627)
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- Species Reactivity: Mouse
- Target: ITGA5
- Application: IHC
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- Anti-Human ITGA5 Immunohistochemistry Kit (VS-0525-XY3629)
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- Species Reactivity: Human, Monkey
- Target: ITGA5
- Application: IHC
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- Anti-Rat ITGA5 Immunohistochemistry Kit (VS-0525-XY3628)
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- Species Reactivity: Human, Mouse, Rat
- Target: ITGA5
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Protein class
Cancer-related genes, CD markers, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Endothelial cells, Hepatic stellate cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (hTERT-RPE1, HUVEC TERT2, TIME, U-87 MG)
Interaction
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with RAB21 and COMP. Interacts with CIB1. ITGA5:ITGB1 interacts with CCN3. ITGA5:ITGB1 interacts with FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 interacts with IL1B (PubMed:29030430). ITGA5:ITGB1 interacts with ACE2 (PubMed:33102950). Interacts with ANGPT2 (PubMed:32908006). (Microbial infection) Integrin ITGA5:ITGB1 interacts with human metapneumovirus fusion protein. (Microbial infection) Integrin ITGA5:ITGB1 interacts with human parvovirus B19 capsid proteins. (Microbial infection) Interacts with HIV-1 Tat. (Microbial infection) ITGA5:ITGB1 interacts with SARS coronavirus-2/SARS-CoV-2 spike protein.
Molecular function
Host cell receptor for virus entry, Integrin, Receptor
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