AbPlus™ Anti-ITGA5 Magnetic Beads (VS-0724-YC1485)

CAT#: VS-0724-YC1485

The AbPlus Anti-ITGA5 Magnetic Beads (VS-0724-YC1485) is an innovative affinity resin which is bound with anti-ITGA5 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ITGA5 protein under native and denaturing conditions.

Gene Expression
Figure 1 High expression in placenta Figure 2 Low expression in skeletal muscle Figure 3 IHC staining of human placenta Figure 4 Liver Figure 5 Placenta Figure 6 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, TIME, U-87 MG)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-ITGA5 specific antibody
  • Target
  • ITGA5
  • Immunogen
  • Recombinant human Integrin alpha 5/CD49e/ITGA5 fragment derived from E. coli.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
  • Alternative Names
  • Integrin Subunit Alpha 5
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