Recombinant Anti-LRRC15 Vesicular Antibody, EV Displayed (VS-0425-YC307)
CAT#: VS-0425-YC307
The Recombinant Anti-LRRC15 Vesicular Antibody, EV Displayed (VS-0425-YC307) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LRRC15-expressed cells or tissues. The LRRC15 binds fibronectin and laminin and is involved in processes like protein localization regulation and viral entry prevention, active in plasma membranes.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/412_C1_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/89507_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/89507_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/89507_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/89507_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/89507_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Non-germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35503/89507_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (fHDF/TERT166, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172061-LRRC15
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LRRC15
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leucine rich repeat containing 15
- Cellular Localization
- Vesicles, Plasma membrane
- Introduction
- Enables several functions, including fibronectin binding activity; laminin binding activity; and protein sequestering activity. Involved in several processes, including negative regulation of protein localization to plasma membrane; negative regulation of viral entry into host cell; and receptor-mediated virion attachment to host cell. Located in collagen-containing extracellular matrix and plasma membrane. Is active in apical plasma membrane.
- Alternative Names
- LIB
- Gene ID
- 131578
- UniProt ID
- Q8TF66
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC307. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LRRC15"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-634-F(E) | Recombinant Anti-human LRRC15 Antibody Fab Fragment | FC, IP, FuncS | Fab |
| MHH-634-F(E) | Recombinant Human Anti-human LRRC15 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| HPAB-0230-WJ-F(E) | Human Anti-LRRC15 Recombinant Antibody; Fab Fragment (HPAB-0230-WJ-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0231-WJ-F(E) | Human Anti-LRRC15 Recombinant Antibody; Fab Fragment (HPAB-0231-WJ-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0232-WJ-F(E) | Human Anti-LRRC15 Recombinant Antibody; Fab Fragment (HPAB-0232-WJ-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-634 | Recombinant Human Anti-human LRRC15 Antibody | WB, IF, FuncS | IgG |
| HPAB-0230-WJ | Human Anti-LRRC15 Recombinant Antibody (HPAB-0230-WJ) | ELISA, FC | Humanized IgG1 |
| HPAB-0231-WJ | Human Anti-LRRC15 Recombinant Antibody (HPAB-0231-WJ) | ELISA, FC | Humanized IgG1 |
| HPAB-0232-WJ | Human Anti-LRRC15 Recombinant Antibody (HPAB-0232-WJ) | ELISA, FC | Humanized IgG1 |
| VS3-FY860 | Recombinant Rabbit Anti-LRRC15 Antibody (clone R04-3E9) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-634-S(P) | Recombinant Human Anti-human LRRC15 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| HPAB-0230-WJ-S(P) | Human Anti-LRRC15 Recombinant Antibody; scFv Fragment (HPAB-0230-WJ-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0231-WJ-S(P) | Human Anti-LRRC15 Recombinant Antibody; scFv Fragment (HPAB-0231-WJ-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0232-WJ-S(P) | Human Anti-LRRC15 Recombinant Antibody; scFv Fragment (HPAB-0232-WJ-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0233-WJ-S(P) | Human Anti-LRRC15 Recombinant Antibody; scFv Fragment (HPAB-0233-WJ-S(P)) | ELISA, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0709CL | Anti-Human LRRC15 Recombinant Antibody | ELISA | |
| TAB-0709CL-S(P) | Anti-Human LRRC15 Recombinant Antibody scFv Fragment | ELISA | |
| TAB-0709CL-F(E) | Anti-Human LRRC15 Recombinant Antibody Fab Fragment | ELISA | |
| MOB-0318MC | Rabbit Anti-Human ALRRC15 polyclonal Antibody | WB, IHC-P, IF, IHC-P |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2090 | Hi-Affi™ Recombinant Rabbit Anti-LRRC15 Monoclonal Antibody (DS2090AB) | WB, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY145 | Mouse Anti-LRRC15 scFv-Fc Chimera (VS-0425-FY145) | ELISA, FC | Mouse IgG1, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: Block, Cyt, FuncS, Inhib
Application: Block, IP, IF, FC
Application: ELISA
-3.jpg)
Application: Neut
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
