Recombinant Anti-MICA Vesicular Antibody, EV Displayed (VS-0425-YC296)
CAT#: VS-0425-YC296
The Recombinant Anti-MICA Vesicular Antibody, EV Displayed (VS-0425-YC296) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MICA-expressed cells or tissues. The MICA is a stress-induced antigen recognized by T cells and is associated with susceptibility to psoriasis and multiple myeloma progression.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, HSkMC, hTERT-RPE1, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204520-MICA
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MICA
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- MHC class I polypeptide-related sequence A
- Introduction
- This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Alternative Names
- PERB11.1
- Gene ID
- 100507436
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Datasheet
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1746-sdAb | Recombinant Anti-Human MICA VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1083z | Mouse Anti-MICA Recombinant Antibody (clone 19F1) | FC, IHC, IP, FuncS | Mouse IgG2a |
| HPAB-M0278-YC | Human Anti-MICA Recombinant Antibody (clone mAb1) | FuncS | Human IgG1 |
| HPAB-M0279-YC | Human Anti-MICA Recombinant Antibody (clone mAb2) | ELISA, FC, Cyt, FuncS | Human IgG1 |
| HPAB-0166-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0166-WJ) | ELISA | Human IgG2a, κ |
| VS-0723-WK247 | Rabbit Anti-MICA Recombinant Antibody (VS-0723-WK247) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-525CL | Human Anti-MICA Recombinant Antibody (TAB-525CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0793CL | Human Anti-MICA Recombinant Antibody (TAB-0793CL) | ELISA, FC | Chimeric (mouse/human) IgG2b |
| TAB-0794CL | Human Anti-MICA Recombinant Antibody (TAB-0794CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| TAB-0795CL | Human Anti-MICA Recombinant Antibody (TAB-0795CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| TAB-0796CL | Human Anti-MICA Recombinant Antibody (TAB-0796CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| TAB-0797CL | Human Anti-MICA Recombinant Antibody (TAB-0797CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0802CL | Human Anti-MICA Recombinant Antibody (TAB-0802CL) | ELISA | Human IgG |
| TAB-0802CL-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0802CL-S(P)) | ELISA | Human scFv |
| TAB-0803CL-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0803CL-S(P)) | ELISA | Human scFv |
| TAB-0802CL-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0802CL-F(E)) | ELISA | Human Fab |
| TAB-0803CL-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0803CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0804CL | Mouse Anti-MICA Recombinant Antibody (TAB-0804CL) | ELISA, FACS | Mouse IgG1 |
| TAB-0804CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0804CL-S(P)) | ELISA | Mouse scFv |
| TAB-0805CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0805CL-S(P)) | ELISA | Mouse scFv |
| TAB-0804CL-F(E) | Mouse Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0804CL-F(E)) | ELISA | Mouse Fab |
| TAB-0805CL-F(E) | Mouse Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0805CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1735CQ | Recombinant Mouse Anti-MICA Antibody (NEUT-1735CQ) | Neut, WB | IgG2 |
| NEUT-1736CQ | Recombinant Mouse Anti-MICA Antibody (CBL144) | Neut, WB | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1737CQ | Recombinant Mouse Anti-MICA Antibody (CBL334) | BL, CyTOF, FC, WB | IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2231 | Hi-Affi™ Recombinant Rabbit Anti-MICA Monoclonal Antibody (DS2231AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0278-YC-S(P) | Human Anti-MICA Recombinant Antibody (clone mAb1); scFv Fragment | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-M0279-YC-S(P) | Human Anti-MICA Recombinant Antibody (clone mAb2); scFv Fragment | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-0166-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0166-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0478-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0478-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0483-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0483-WJ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0278-YC-F(E) | Human Anti-MICA Recombinant Antibody (clone mAb1); Fab Fragment | ELISA, FC, Cyt, FuncS | Human Fab |
| HPAB-M0279-YC-F(E) | Human Anti-MICA Recombinant Antibody (clone mAb2); Fab Fragment | ELISA, FC, Cyt, FuncS | Human Fab |
| HPAB-0478-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0478-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0483-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0483-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0484-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0484-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1023 | AbPlus™ Anti-MICA Magnetic Beads (VS-0724-YC1023) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4389 | Anti-MICA Immunohistochemistry Kit | IHC | |
| VS-0525-XY4390 | Anti-Mouse MICA Immunohistochemistry Kit | IHC |
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