Human Anti-MICA Recombinant Antibody (clone mAb1); Fab Fragment (CAT#: HPAB-M0278-YC-F(E))
Provided is an antibody capable of binding to human MICA polypeptides. The antibody has increased activity in the treatment of disorders characterized by MICA-expressing cells, particularly cancer. mAb1 and mAb2 showed a particularly strong improvement in binding affinity for MICA alleles *01, *04 and *07.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, HSkMC, hTERT-RPE1, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204520-MICA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204520-MICA
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human MICA
- Species Reactivity
- Human
- Clone
- mAb1
- Applications
- ELISA, FC, Cyt, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MHC Class I Polypeptide-Related Sequence A; PERB11.1; MIC-A; Truncated MHC Class I Polypeptide-Related Sequence A; MHC Class I Chain-Related Protein A; Stress Inducible Class I Homolog; MHC Class I Related Sequence A; MHC Class I Related Chain A; HLA Class I Antigen;
- Gene ID
- 100507436
- UniProt ID
- Q29983
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone mAb1"
See other products for "MICA"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1746-sdAb | Recombinant Anti-Human MICA VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1083z | Mouse Anti-MICA Recombinant Antibody (clone 19F1) | FC, IHC, IP, FuncS | Mouse IgG2a |
| HPAB-0166-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0166-WJ) | ELISA | Human IgG2a, κ |
| HPAB-0478-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0478-WJ) | ELISA | Human IgG |
| HPAB-0483-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0483-WJ) | ELISA | Human IgG |
| HPAB-0484-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0484-WJ) | ELISA | Human IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-525CL | Human Anti-MICA Recombinant Antibody (TAB-525CL) | ELISA | Human IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0802CL | Human Anti-MICA Recombinant Antibody (TAB-0802CL) | ELISA | Human IgG |
| TAB-0803CL | Human Anti-MICA Recombinant Antibody (TAB-0803CL) | ELISA | Human IgG |
| TAB-0802CL-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0802CL-S(P)) | ELISA | Human scFv |
| TAB-0802CL-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0802CL-F(E)) | ELISA | Human Fab |
| TAB-0803CL-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0803CL-F(E)) | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0804CL | Mouse Anti-MICA Recombinant Antibody (TAB-0804CL) | ELISA, FACS | Mouse IgG1 |
| TAB-0804CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0804CL-S(P)) | ELISA | Mouse scFv |
| TAB-0805CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0805CL-S(P)) | ELISA | Mouse scFv |
| TAB-0804CL-F(E) | Mouse Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0804CL-F(E)) | ELISA | Mouse Fab |
| TAB-0805CL-F(E) | Mouse Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0805CL-F(E)) | ELISA | Mouse Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0793CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0793CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-0794CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0794CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-0795CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0795CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-0796CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0796CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-0797CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0797CL-S(P)) | ELISA, FC | Mouse scFv |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1735CQ | Recombinant Mouse Anti-MICA Antibody (13M21) | Neut, WB | IgG2 |
| NEUT-1736CQ | Recombinant Mouse Anti-MICA Antibody (CBL144) | Neut, WB | IgG2 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1737CQ | Recombinant Mouse Anti-MICA Antibody (CBL334) | BL, CyTOF, FC, WB | IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2231 | Hi-Affi™ Recombinant Rabbit Anti-MICA Monoclonal Antibody (DS2231AB) | WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0278-YC-S(P) | Human Anti-MICA Recombinant Antibody (clone mAb1); scFv Fragment | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-0166-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0166-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0478-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0478-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0483-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0483-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0484-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0484-WJ-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0279-YC-F(E) | Human Anti-MICA Recombinant Antibody (clone mAb2); Fab Fragment | ELISA, FC, Cyt, FuncS | Human Fab |
| HPAB-0166-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0166-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0478-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0478-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0483-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0483-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0484-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0484-WJ-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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