Human Anti-MICA Recombinant Antibody (clone mAb2); Fab Fragment
CAT#: HPAB-M0279-YC-F(E)
Provided is an antibody capable of binding to human MICA polypeptides. The antibody has increased activity in the treatment of disorders characterized by MICA-expressing cells, particularly cancer. mAb1 and mAb2 showed a particularly strong improvement in binding affinity for MICA alleles *01, *04 and *07.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, HSkMC, hTERT-RPE1, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204520-MICA
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Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human MICA
- Species Reactivity
- Human
- Clone
- mAb2
- Applications
- ELISA, FC, Cyt, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MHC Class I Polypeptide-Related Sequence A; PERB11.1; MIC-A; Truncated MHC Class I Polypeptide-Related Sequence A; MHC Class I Chain-Related Protein A; Stress Inducible Class I Homolog; MHC Class I Related Sequence A; MHC Class I Related Chain A; HLA Class I Antigen;
- Gene ID
- 100507436
- UniProt ID
- Q29983
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone mAb2"
- CAT
- Product Name
See other products for "MICA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1746-sdAb | Recombinant Anti-Human MICA VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-525CL | Human Anti-MICA Recombinant Antibody (TAB-525CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0793CL | Human Anti-MICA Recombinant Antibody (TAB-0793CL) | ELISA, FC | Chimeric (mouse/human) IgG2b |
| TAB-0794CL | Human Anti-MICA Recombinant Antibody (TAB-0794CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| TAB-0795CL | Human Anti-MICA Recombinant Antibody (TAB-0795CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| TAB-0796CL | Human Anti-MICA Recombinant Antibody (TAB-0796CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| TAB-0797CL | Human Anti-MICA Recombinant Antibody (TAB-0797CL) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0802CL | Human Anti-MICA Recombinant Antibody (TAB-0802CL) | ELISA | Human IgG |
| TAB-0803CL | Human Anti-MICA Recombinant Antibody (TAB-0803CL) | ELISA | Human IgG |
| TAB-0802CL-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0802CL-S(P)) | ELISA | Human scFv |
| TAB-0803CL-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0803CL-S(P)) | ELISA | Human scFv |
| TAB-0802CL-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0802CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0804CL | Mouse Anti-MICA Recombinant Antibody (TAB-0804CL) | ELISA, FACS | Mouse IgG1 |
| TAB-0805CL | Mouse Anti-MICA Recombinant Antibody (TAB-0805CL) | ELISA, FACS | Mouse IgG1 |
| TAB-0804CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0804CL-S(P)) | ELISA | Mouse scFv |
| TAB-0805CL-S(P) | Mouse Anti-MICA Recombinant Antibody; scFv Fragment (TAB-0805CL-S(P)) | ELISA | Mouse scFv |
| TAB-0804CL-F(E) | Mouse Anti-MICA Recombinant Antibody; Fab Fragment (TAB-0804CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1735CQ | Recombinant Mouse Anti-MICA Antibody (NEUT-1735CQ) | Neut, WB | IgG2 |
| NEUT-1736CQ | Recombinant Mouse Anti-MICA Antibody (CBL144) | Neut, WB | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1737CQ | Recombinant Mouse Anti-MICA Antibody (CBL334) | BL, CyTOF, FC, WB | IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2231 | Hi-Affi™ Recombinant Rabbit Anti-MICA Monoclonal Antibody (DS2231AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0278-YC | Human Anti-MICA Recombinant Antibody (clone mAb1) | FuncS | Human IgG1 |
| HPAB-M0279-YC | Human Anti-MICA Recombinant Antibody (clone mAb2) | ELISA, FC, Cyt, FuncS | Human IgG1 |
| HPAB-0478-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0478-WJ) | ELISA | Human IgG |
| HPAB-0483-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0483-WJ) | ELISA | Human IgG |
| HPAB-0484-WJ | Human Anti-MICA Recombinant Antibody (HPAB-0484-WJ) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0278-YC-S(P) | Human Anti-MICA Recombinant Antibody (clone mAb1); scFv Fragment | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-M0279-YC-S(P) | Human Anti-MICA Recombinant Antibody (clone mAb2); scFv Fragment | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-0166-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0166-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0478-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0478-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0483-WJ-S(P) | Human Anti-MICA Recombinant Antibody; scFv Fragment (HPAB-0483-WJ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0278-YC-F(E) | Human Anti-MICA Recombinant Antibody (clone mAb1); Fab Fragment | ELISA, FC, Cyt, FuncS | Human Fab |
| HPAB-0166-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0166-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0478-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0478-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0483-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0483-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0484-WJ-F(E) | Human Anti-MICA Recombinant Antibody; Fab Fragment (HPAB-0484-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1023 | AbPlus™ Anti-MICA Magnetic Beads (VS-0724-YC1023) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC296 | Recombinant Anti-MICA Vesicular Antibody, EV Displayed (VS-0425-YC296) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4389 | Anti-MICA Immunohistochemistry Kit | IHC | |
| VS-0525-XY4390 | Anti-Mouse MICA Immunohistochemistry Kit | IHC |
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