Human Anti-MICA Recombinant Antibody (clone mAb1); scFv Fragment (CAT#: HPAB-M0278-YC-S(P))
Provided is an antibody capable of binding to human MICA polypeptides. The antibody has increased activity in the treatment of disorders characterized by MICA-expressing cells, particularly cancer. mAb1 and mAb2 showed a particularly strong improvement in binding affinity for MICA alleles *01, *04 and *07.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, HSkMC, hTERT-RPE1, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204520-MICA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204520-MICA
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human MICA
- Species Reactivity
- Human
- Clone
- mAb1
- Applications
- ELISA, FC, Cyt, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MHC Class I Polypeptide-Related Sequence A; PERB11.1; MIC-A; Truncated MHC Class I Polypeptide-Related Sequence A; MHC Class I Chain-Related Protein A; Stress Inducible Class I Homolog; MHC Class I Related Sequence A; MHC Class I Related Chain A; HLA Class I Antigen;
- Gene ID
- 100507436
- UniProt ID
- Q29983
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1746-sdAb | Recombinant Anti-Human MICA VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
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