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    Recombinant Human Anti-NECTIN4 Antibody (clone 6D3) (CAT#: VS4-CJ51)

    This human anti-NECTIN4 antibody (clone 6D3) is a product that recognizes human NECTIN4. The immunogen of this antibody is recombinant human NECTIN4 protein. The mAb has been tested for use in ELISA.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/1671_G1_2_selected.jpg
    Normal Tissue
    Figure 2 Skin 1
    Figure 2 Skin 1
    (High expression in skin 1)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_B_9_1_val_selected.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_A_9_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_A_9_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_A_6_6.jpg
    Figure 6 Skin
    Figure 6 Skin
    (Epidermal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_B_5_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (BEWO, HaCaT, MCF7, OE19, SK-BR-3, T-47d)
    Figure 7 RNA cell line category: Cell line enhanced (BEWO, HaCaT, MCF7, OE19, SK-BR-3, T-47d)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143217-NECTIN4

    Specifications

    • Immunogen
    • Recombinant Human NECTIN4 protein
    • Host Species
    • Human
    • Type
    • Human IgG1
    • Specificity
    • Human NECTIN4
    • Species Reactivity
    • Human
    • Clone
    • 6D3
    • Applications
    • ELISA
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Affinity chromatography
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • 50% Glycerol, 0.01M PBS, pH 7.4.
    • Preservative
    • 0.03% Proclin 300
    • Storage
    • Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

    Applications

    • Application Notes
    • This antibody has been tested for use in ELISA.

    Target

    • Alternative Names
    • LNIR; PRR4; EDSS1; PVRL4; nectin-4
    • Long Name
    • Nectin cell adhesion molecule 4
    • Sequence Similarities
    • Belongs to the nectin family.
    • Cellular Localization
    • Cell junction, Cell membrane, Membrane, Secreted
    • Post Translation Modifications
    • The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.
    • Function
    • Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.
      (Microbial infection) Acts as a receptor for measles virus.

    Recommended Products

    Isotype Control

    Secondary Antibody

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "NECTIN4"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Human Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-H25 Human Anti-NECTIN4 Recombinant Antibody (TAB-H25) ELISA, Neut, IF, IP, FC, FuncS Human IgG1, κ

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