Recombinant Human Anti-NECTIN4 Antibody (clone 6D3)
CAT#: VS4-CJ51
This human anti-NECTIN4 antibody (clone 6D3) is a product that recognizes human NECTIN4. The immunogen of this antibody is recombinant human NECTIN4 protein. The mAb has been tested for use in ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/1671_G1_2_selected.jpg
Normal Tissue
Figure 2 Skin 1
High expression in skin 1
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_B_9_1_val_selected.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_A_6_6.jpg
Normal Tissue
Figure 6 Skin
Epidermal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10775/27075_B_5_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (BEWO, HaCaT, MCF7, OE19, SK-BR-3, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143217-NECTIN4
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Specifications
- Immunogen
- Recombinant Human NECTIN4 protein
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human NECTIN4
- Species Reactivity
- Human
- Clone
- 6D3
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.01M PBS, pH 7.4.
- Preservative
- 0.03% Proclin 300
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA.
Target
- Alternative Names
- LNIR; PRR4; EDSS1; PVRL4; nectin-4
- Gene ID
- 81607
- UniProt ID
- Q96NY8
- Long Name
- Nectin cell adhesion molecule 4
- Sequence Similarities
- Belongs to the nectin family.
- Cellular Localization
- Cell junction, Cell membrane, Membrane, Secreted
- Post Translation Modifications
- The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.
- Protein Refseq
- NP_112178.2
- Function
- Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.
(Microbial infection) Acts as a receptor for measles virus.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "NECTIN4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H25 | Human Anti-NECTIN4 Recombinant Antibody (TAB-H25) | ELISA, Neut, IF, IP, FC, FuncS | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0034-DJB | Mouse Anti-NECTIN4 Recombinant Antibody (clone N41) | ELISA, IHC, FC | Mouse IgG |
| VS-0723-WK124 | Human Anti-NECTIN4 Recombinant Antibody (VS-0723-WK124) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0034-DJB-S(P) | Mouse Anti-NECTIN4 Recombinant Antibody (clone N41); scFv Fragment | ELISA, IHC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0034-DJB-F(E) | Mouse Anti-NECTIN4 Recombinant Antibody (clone N41); Fab Fragment | ELISA, IHC, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY114 | Human Anti-NECTIN4 (clone Enfortumab) scFv-Fc Chimera | ELISA, Neut, IF, IP, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC71 | Recombinant Anti-NECTIN4 Vesicular Antibody, EV Displayed (VS-0425-YC71) | ELISA, FC, Neut, Cell-uptake |
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