Human Anti-NECTIN4 (clone Enfortumab) scFv-Fc Chimera (CAT#: VS-0325-FY114)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Specificity
• Human NECTIN4

• Species Reactivity
• Human

• Clone
• Enfortumab

• Applications
• ELISA, Neutralization, Immunofluorescence, Immunoprecipitation, Flow Cytometry

• Related Disease
• Cancer

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• Nectin Cell Adhesion Molecule 4; Poliovirus Receptor-Related Protein 4; Poliovirus Receptor-Related 4; Ig Superfamily Receptor LNIR; PVRL4; LNIR

• Gene ID
• 81607

• UniProt ID
• Q96NY8

• Long Name
• Nectin Cell Adhesion Molecule 4

• Sequence Similarities
• Belongs to the nectin family.

• Cellular Localization
• Cell junction; Cell membrane; Membrane; Secreted

• Post Translation Modifications
• The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.

• Protein Refseq
• NP_112178.2

• Function
• Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.
  (Microbial infection) Acts as a receptor for measles virus.

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

• ADC-L004
• Anti-Nectin-4 (Enfortumab)-mc-val-cit-PABC-MMAE ADC (AGS-22ME)

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