Recombinant Mouse Anti-NEFL Antibody (clone 2D7-6C10-10B2) (CAT#: VS3-FY1026)
This product is a recombinant mouse antibody that recognizes NEFL. This antibody has been reported for use in Immunohistochemistry-Paraffin. The clone 2D7-6C10-10B2 is specific for human NEFL. The antigen is synthetic peptides derived from human neurofilament.
Specific Inquiry
IHC-P
Figure 1. Recombinant Mouse Anti-NEFL Antibody (clone 2D7-6C10-10B2) in IHC-P.
Immunohistochemical analysis of paraffin-embedded brain using Neurofilament Light Polypeptide Antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
Specifications
- Immunogen
- Synthetic peptides derived from human neurofilament.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human NEFL
- Species Reactivity
- Human
- Clone
- 2D7-6C10-10B2
- Applications
- Immunohistochemistry-Paraffin
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS, pH 7.3, 50% glycerol, 0.5% BSA
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry-Paraffin: 1/100-1/500
Target
- Alternative Names
- Neurofilament Light; Protein Phosphatase 1, Regulatory Subunit 110; Neurofilament, Light Polypeptide 68kDa; Neurofilament Triplet L Protein; NF-L; NF68; NFL; Light Molecular Weight Neurofilament Protein; Neurofilament Protein, Light Chain
- Gene ID
- 4747
- UniProt ID
- P07196
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Cell projection, Cytoplasm, Cytoskeleton, Intermediate filament
- Post Translation Modifications
- O-glycosylated.
Phosphorylated in the head and rod regions by the PKC kinase PKN1, leading to the inhibition of polymerization.
Ubiquitinated in the presence of TRIM2 and UBE2D1.
- Protein Refseq
- NP_006149.2
- Function
- Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "NEFL"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2006z | Mouse Anti-NEFL Recombinant Antibody (clone 32C12) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MOB-1158CT | Recombinant Mouse anti-Rat NEFL Monoclonal antibody (2E3) | ICC/IF, IHC-Fr, IHC-P, WB | |
| ZG-0563F | Mouse Anti-NEFL Recombinant Antibody (clone 2F11) | IHC-Fr, IHC-P, IB | Mouse IgG1 |
| VS3-XY1150 | Mouse Anti-NEFL Recombinant Antibody (clone 2G10) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS3-FY1025 | Recombinant Rabbit Anti-Nefl Antibody (clone R04-7H3) | WB, IHC-P, IP | Rabbit IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0822MZ | Chicken Anti-NEFL Polyclonal IgY | ICC, IF, IHC, WB | Chicken antibody |
| BRD-1153MZ | Chicken Anti-Neurofilament Light Polyclonal IgY | WB, ICC | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2411 | Hi-Affi™ Recombinant Rabbit Anti-NEFL Monoclonal Antibody (DS2411AB) | WB, IP, FC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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