Recombinant Anti-NRP2 Vesicular Antibody, EV Displayed (VS-0425-YC360) (CAT#: VS-0425-YC360)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• NRP2

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Neuropilin 2

• Biological Process
• Differentiation, Host-virus interaction, Neurogenesis

• Molecular Function
• Developmental protein, Heparin-binding, Receptor

• Cellular Localization
• Vesicles, Plasma membrane, Nucleoplasm

• Introduction
• This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

• Alternative Names
• VEGF165R2

• Gene ID
• 8828

• UniProt ID
• O60462

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