Human Anti-NRP2 Recombinant Antibody; Fab Fragment (CAT#: PFBW-095)
Recombinant Human Antibody is capable of binding to NRP2 a1a2b1b2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-NRP2 a1a2b1b2 fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-NRP2 a1a2b1b2 fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody blocks Sema3 binding and function meditated through both Nrp1 and Nrp2 in vitro.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54974/1559_D5_5_selected.jpg

(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane & nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54974/985_C1_1_blue_red_green.jpg

(Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_B_7_5.jpg

(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_A_9_3.jpg

(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_A_6_6.jpg

(Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_B_6_7.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118257-NRP2
Specifications
- Immunogen
- Human neuropilin 2
- Host Species
- Human
- Derivation
- Human
- Type
- Human Fab
- Specificity
- Human NRP2
- Species Reactivity
- Human
- Applications
- Block
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- NRP2; neuropilin 2; NP2; NPN2; PRO2714; VEGF165R2; neuropilin-2; neuropilin-2b(0); neuropilin-2a(17); neuropilin-2a(22); receptor for VEGF165 and semaphorins class3; vascular endothelial cell growth factor 165 receptor 2
- Gene ID
- 8828
- UniProt ID
- O60462
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "NRP2"
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1810-VHH | Recombinant Anti-Human NRP2 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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