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    Anti-Human NRP2 Recombinant Antibody Fab Fragment (ITAC-B1) (CAT#: TAB-0152CL-F(E))

    The anti-NRP2 antibody against the VEGF-binding site of B domain of NRP-2 and therefore reduces tumor lymphangiogenesis and the formation of metastases, increase p53 expression, induces apoptosis of tumour cells. Thus, it can be used in the anticancer treatment, such as colorectal cancer, breast cancer, kidney cancer, melanomas.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54974/1559_D5_5_selected.jpg
    Figure 2 IF staining of human cell line A549
    Figure 2 IF staining of human cell line A549
    (Immunofluorescent staining of human cell line A549 shows localization to plasma membrane & nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54974/985_C1_1_blue_red_green.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_A_9_3.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_A_6_6.jpg
    Figure 6 Smooth muscle
    Figure 6 Smooth muscle
    (Smooth muscle cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_B_6_7.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HUVEC TERT2, TIME, U-251 MG)
    Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HUVEC TERT2, TIME, U-251 MG)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118257-NRP2

    Specifications

    • Immunogen
    • P815-NRP-2 transfected cell
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Clone
    • ITAC-B1
    • Related Disease
    • Colorectal cancer, breast cancer, kidney cancer, melanomas

    Target

    • Alternative Names
    • NRP2; neuropilin 2; NP2; NPN2; PRO2714; VEGF165R2; neuropilin-2; neuropilin-2b(0); neuropilin-2a(17); neuropilin-2a(22); receptor for VEGF165 and semaphorins class3; vascular endothelial cell growth factor 165 receptor 2;

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Please select product type
    Single Domain Antibody Products IgG Antibody Products Immunotoxin Products Fab Antibody Products ScFv Antibody Products Mouse Antibody Products Chicken IgY Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    NAB-1810-VHH Recombinant Anti-Human NRP2 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH

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