Recombinant Rabbit Anti-PRSS2 Antibody (clone 12H7) (CAT#: VS4-CJ94)

• Immunogen
• A synthesized peptide derived from human PRSS2

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human PRSS2

• Species Reactivity
• Human

• Clone
• 12H7

• Applications
• ELISA, IF

• Conjugate
• Unconjugated

• Purification
• Affinity chromatography

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.

• Preservative
• 0.02% Sodium Azide

• Storage
• Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

• Application Notes
• This antibody has been tested for use in ELISA, Immunofluorescence (1:50-1:200).

• Alternative Names
• TRY2; TRY8; TRYP2

• Gene ID
• 5645

• UniProt ID
• P07478

• Long Name
• Serine protease 2

• Sequence Similarities
• Belongs to the peptidase S1 family.

• Cellular Localization
• Secreted

• Post Translation Modifications
• Sulfated on tyrosine.
  Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins.

• Protein Refseq
• NP_002761.1

• Function
• In the ileum, may be involved in defensin processing, including DEFA5.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-057CQ
• Donkey Anti-Rabbit IgG (H&L) Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS