Recombinant Rabbit Anti-SLC25A12 Antibody (clone 10B12) (CAT#: VS4-CJ114)

• Immunogen
• A synthesized peptide derived from human SLC25A12

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human SLC25A12

• Species Reactivity
• Human

• Clone
• 10B12

• Applications
• ELISA, WB

• Conjugate
• Unconjugated

• Purification
• Affinity chromatography

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.

• Preservative
• 0.02% Sodium Azide

• Storage
• Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

• Application Notes
• This antibody has been tested for use in ELISA, Western Blot (1:500-1:2000).

• Alternative Names
• AGC1; DEE39; ARALAR; EIEE39

• Gene ID
• 8604

• UniProt ID
• O75746

• Long Name
• Solute carrier family 25 member 12

• Sequence Similarities
• Belongs to the mitochondrial carrier (TC 2.A.29) family.

• Cellular Localization
• Membrane, Mitochondrion, Mitochondrion inner membrane

• Protein Refseq
• NP_003696.2

• Function
• Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:19641205, PubMed:24515575).
  Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (PubMed:11566871).

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-057CQ
• Donkey Anti-Rabbit IgG (H&L) Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

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