Recombinant Anti-Tacr1 Vesicular Antibody, EV Displayed (VS-0425-YC744) (CAT#: VS-0425-YC744)

• Application
• ELISA, FC, Inhib, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• Tacr1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Rat

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Tachykinin receptor 1

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Plasma membrane, Centrosome, Basal body

• Introduction
• Enables substance P receptor activity. Involved in several processes, including learning or memory; positive regulation of cell communication; and regulation of cell migration. Located in cell body; cell surface; and dendrite. Is active in postsynaptic membrane. Used to study central sleep apnea; cystitis; pancreatitis; and pulmonary hypertension. Biomarker of acute necrotizing pancreatitis; allergic rhinitis; asthma; colitis; and respiratory syncytial virus infectious disease. Human ortholog(s) of this gene implicated in developmental disorder of mental health and exercise-induced bronchoconstriction. Orthologous to human TACR1 (tachykinin receptor 1).

• Alternative Names
• Tac1r

• Gene ID
• 24807

• UniProt ID
• P14600

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