Mouse Anti-TACR1 Recombinant Antibody (clone 6) (CAT#: FAMAB-0218JF)

Recombinant monoclonal antibody specially binds to the ligand-binding domain of the neurokinin 1 receptor for the neuropeptide substance P. This mouse anti-neurokinin 1 receptor antibody (clone 6) can be widely used in the study of the mechanism of various diseases of the central nervous system, sunch as schizophrenia, migraine, fibromyalgia.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 NK1 is present in BMSCs, murine osteoblast-like MC3T3-E1 cells, and mouse brain.

Figure 1 NK1 is present in BMSCs, murine osteoblast-like MC3T3-E1 cells, and mouse brain.

Laser scanning confocal microscopy of mouse bone marrow stromal cells (BMSCs).

Wang, L., Zhao, R., Shi, X., Wei, T., Halloran, B. P., Clark, D. J., ... & Kingery, W. S. (2009). Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone, 45(2), 309-320.

IHC

Figure 2 The homogeneous presence of red fluorescence indicates the presence of NK1 receptors.

Figure 2 The homogeneous presence of red fluorescence indicates the presence of NK1 receptors.

Alkaline phosphatase and the substance P (SP) NK1 receptors were co-localized in the cytoplasm and on the plasma membrane of BMSCs.

Wang, L., Zhao, R., Shi, X., Wei, T., Halloran, B. P., Clark, D. J., ... & Kingery, W. S. (2009). Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone, 45(2), 309-320.


Specifications

  • Immunogen
  • PS5 (sequence HQSKELLRLGS) conjugate emulsified with Freund's complete adjuvant
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • Rat TACR1
  • Species Reactivity
  • Rat
  • Clone
  • 6
  • Applications
  • WB, IHC
  • Related Disease
  • Schizophrenia, Migraine, Fibromyalgia

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The TACR1 antibody has been reported in applications of Western Blot, Immunohistochemistry.

Target

  • Alternative Names
  • Spr; Nk1r; Tac1r

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 6"

See other products for "TACR1"

Rabbit Monoclonal Antibody

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for FAMAB-0218JF. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare