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BID
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Anti-BID Products
- Rabbit Anti-BID Recombinant Antibody (clone JM11-14) (MRO-0179-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
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- Mouse Anti-BID Recombinant Antibody (VS3-CJ1050) (VS3-CJ1050)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ICC, IHC
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- Rabbit Anti-BID Recombinant Antibody (clone R08-2F0) (VS3-FY1976)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, IF, IP
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- Rat Anti-BID Agonistic Antibody (VS-0724-XY4) (VS-0724-XY4)
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- Species Reactivity: Human, Mouse
- Type: Rat IgG1
- Application: WB
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- AbPlus™ Anti-BID Magnetic Beads (VS-0724-YC630) (VS-0724-YC630)
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- Target: BID
- Target Species: Human
- Application: IP, Protein Purification
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- AbPlus™ Anti-Bid Magnetic Beads (VS-0724-YC751) (VS-0724-YC751)
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- Target: Bid
- Target Species: Mouse
- Application: IP, Protein Purification
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- Mouse Anti-BID Recombinant Antibody (clone 19H5) (MOB-2323z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, IF, IHC
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- Mouse Anti-BID Recombinant Antibody (clone 4D6) (MOB-2266MZ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC, IF, IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, IF, IHC-P, IP, WB
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- Mouse Anti-BID Recombinant Antibody (clone 3C5) (VS7-HM229)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FCM
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-p, IF, ICC, FCM, ELISA
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- Anti-BID Immunohistochemistry Kit (VS-0325-XY243)
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- Species Reactivity: Human
- Target: BID
- Application: IHC
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- Anti-Human BID Immunohistochemistry Kit (VS-0525-XY768)
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- Species Reactivity: Human
- Target: BID
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Langerhans cells, monocytes, Basal respiratory cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (MCF7)
Interaction
Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2 (By similarity). Interacts with PLEKHN1 (PubMed:29531808). [BH3-interacting domain death agonist]: Interacts with humanin; forms fibers with humanin which results in BID conformational changes and sequestering of BID into the fibers, preventing BID activation. [BH3-interacting domain death agonist p15]: Interacts with ITCH (PubMed:20392206). Interacts with humanin; the interaction prevents BID-induced apoptosis (PubMed:15661737). Interacts with MTCH2 (By similarity).
More Types Infomation
Related Signaling Pathways
p53 Signaling Pathway
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