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CAMK2D
CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) is a Protein Coding gene. Diseases associated with CAMK2D include Dilated Cardiomyopathy. Among its related pathways are RET signaling and Salivary secretion. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2B.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Oligodendrocyte precursor cells, Inhibitory neurons, Microglial cells, Excitatory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (ASC TERT1)
Interaction
CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other (PubMed:14722083). Interacts with RRAD and CACNB2 (By similarity).
Molecular function
Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
Canonical Wnt Signaling Pathway
ErbB Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Related Diseases
Amphetamine Addiction
Cushing Syndrome
- Rabbit Anti-CAMK2D Recombinant Antibody (clone JA30-07) (MRO-0226-CN)
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- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, IHC
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IHC-P
- Rabbit Anti-CAMK2D Polyclonal Antibody (MRO-1714-CN) (MRO-1714-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC, WB
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.