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Anti-CAMK2G Recombinant Antibody Products

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Anti-CAMK2G Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs, a world-renowned research supplier, offers high-quality anti-CAMK2G recombinant antibodies for your cell signaling projects. The CAMK2G is the most ubiquitously expressed isoform in the CAMKII family. A calcium/calmodulin-dependent protein kinase, CAMK2G is a multifunctional enzyme that plays a role in a host of physiologic processes from smooth muscle contraction to immune cell signaling. Our recombinant antibodies to CAMK2G are the best tools for investigating the physiologic relevance of this versatile kinase and its potential roles in disease.

CAMK2G: The Ubiquitous CAMKII Isoform

Calcium/Calmodulin-Dependent Protein Kinase II Gamma (CAMK2G) is a member of the CAMKII family of serine/threonine kinases. CAMK2G is different from the other isoforms in the family in that it is expressed in a wide variety of cell types, such as smooth muscle cells, lymphocytes, and neurons. Once activated by calcium/calmodulin, CAMK2G phosphorylates multiple substrates and regulates diverse cellular functions. For instance, it participates in the regulation of smooth muscle contraction, and it has also been reported to play an essential role in T-cell activation and cytokine production.

Alternative Names

CAMK, CAMK-II, CAMKG, MRD59

Background

Calcium/Calmodulin-Dependent Protein Kinase II Gamma is one of the four subunits of an enzyme that belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling has been implicated in several aspects of plasticity at glutamatergic synapses. The mammalian enzyme is made up of four chains that are known as alpha, beta, gamma and delta. The gene product is a gamma chain. Many alternatively spliced transcripts that encode different isoforms have been described but the full-length nature of all the variants has not been determined.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Astrocytes, Cytotrophoblasts)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Cell line enhanced (PC-3, SK-BR-3)

Interaction

CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other.

Molecular function

Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase

More Types Infomation

Anti-CAMK2G rAb Products

Creative Biolabs' anti-CAMK2G recombinant antibodies (rAbs) are designed to provide unsurpassed specificity and performance for the most demanding research applications. Our recombinant antibodies to CAMK2G are extensively validated to detect the gamma isoform in various cell/tissue lysates with limited cross-reactivity to other CAMKII isoforms. Engineered for use in robust applications like Western Blot and IHC, our rAbs to CAMK2G are an indispensable tool for examining the numerous and diverse functions of this ubiquitous kinase.

Table 1. Featured anti-CAMK2G recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
MOB-2331z Mouse Anti-CAMK2G Recombinant Antibody (clone 28F3) Human Mouse IgG1 WB, ELISA, FC, ICC, IF, IHC
VS3-QX147 Mouse Anti-CAMK2G Recombinant Antibody (clone 3D1-G8-D5) Human, Rat Mouse IgG1 WB, IHC, ICC, FC, ELISA
VS3-WK1344 Rabbit Anti-CAMK2G Recombinant Antibody (VS3-WK1344) Human, Mouse, Rat Rabbit IgG WB, ICC, IF, IHC-P

Customer Reviews

Excellent
S**ah
Mouse Anti-CAMK2G Recombinant Antibody (clone 28F3)
The lot-to-lot consistency of Creative Biolabs' antibodies is excellent. We have been using their anti-CAMK2G antibody for Western blots in our long-term signaling studies and it has provided consistent results over several years.
11/Jul/2024

rAb Production

Creative Biolabs is dedicated to advancing the development of next-generation therapeutics. We use proprietary, cutting-edge platforms to produce your recombinant antibodies. Our anti-CAMK2G recombinant antibodies are produced in an optimized system, and they are confirmed to recognize the native form of the protein, so you can be confident that you will receive a highly functional product for your research.

Featured Anti-CAMK2G Recombinant Antibody Production PlatformsFig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-CAMK2G recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-CAMK2G recombinant antibody production.

rAb Modalities

Creative Biolabs is passionate about offering innovative solutions to meet the needs of the cell biology research community. Our recombinant antibodies to CAMK2G are available in a variety of customizable formats so you can easily find the right antibody modalities for your research needs.

Fig.3 CAMK2G antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-CAMK2G recombinant antibody production and modalities.

Target CAMK2G with Creative Biolabs' premium anti-CAMK2G recombinant antibodies. Our products have the specificity and functional activity to enable you to study this ubiquitous CAMKII isoform. Rely on our expertise to provide a robust foundation for the next generation of therapeutics. Contact our scientific team today.

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