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CCR7

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For Research Use Only. Not For Clinical Use.


Background

CCR7 (C-C Motif Chemokine Receptor 7) is a Protein Coding gene. Diseases associated with CCR7 include Chronic Actinic Dermatitis and Pars Planitis. Among its related pathways are Akt Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine (C-C motif) ligand 19 binding. An important paralog of this gene is CCR9.
Protein class

Cancer-related genes, CD markers, G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Group enriched (monocytes, Syncytiotrophoblasts, Langerhans cells)

Immune cell specificity

Immune cell enhanced (naive CD4 T-cell)

Cell line specificity

Cell line enriched (HDLM-2)

Molecular function

G-protein coupled receptor, Receptor, Transducer

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