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CXCL1

Anti-CXCL1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
Protein class

Cancer-related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Basal respiratory cells, Club cells, Ionocytes)

Immune cell specificity

Immune cell enriched (neutrophil)

Cell line specificity

Group enriched (BJ hTERT+, EFO-21, RPTEC TERT1)

Molecular function

Cytokine, Growth factor

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