EGFR & FcγRI
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Loading...- A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer (MHC-LC773)
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- Class: Class I
- Antigen: EGFR
- Antigen Species: Human
- Peptide: YLNTVQPTCV
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
EGFR: Functions as a receptor tyrosine kinase controlling cell growth and differentiation. It activates multiple signaling cascades upon ligand binding. The protein is widely expressed in epithelial tissues. Mutations drive oncogenesis.
Related Diseases
Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
Related Signaling Pathways
JAK-STAT Signaling Pathway