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EGFR & FcγRI

Anti-EGFR & FcγRI Products

A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer (MHC-LC773)
- Class: Class I
- Antigen: EGFR
- Antigen Species: Human
- Peptide: YLNTVQPTCV
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PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer (MHC-LC4545)
- Class: Class II
- Antigen: EGFR
- Antigen Species: Human
- Peptide: SRALEEKKGNYVVTHG
- Conjugate: PE
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A*02:01/Human EGF-R-479 (KLFGTSGQKT) MHC Pentamer (MHC-YF409)
- Class: Class I
- Antigen: EGF-R-479
- Antigen Species: Human
- Peptide: KLFGTSGQKT
- Conjugate: Unlabeled, Biotin, R-PE, APC
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For Research Use Only. Not For Clinical Use.

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.

Related Diseases

Bladder Cancer

Non-small Cell Lung Cancer

Pancreatic Cancer

Hepatocellular Carcinoma

Cushing Syndrome

Related Signaling Pathways

JAK-STAT Signaling Pathway