PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer (CAT#: MHC-LC4545)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human EGFR of peptide SRALEEKKGNYVVTHG and DQB1*03:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Allele
  • DQB1*03:02
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • EGFR
  • Antigen Species
  • Human
  • Peptide
  • SRALEEKKGNYVVTHG
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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