PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer

Name: PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer
SKU: MHC-LC4545
Rating: 5 (1 reviews)

CAT#: MHC-LC4545

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human EGFR of peptide SRALEEKKGNYVVTHG and DQB1*03:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg

Subcellular Location and Protein Expression Figure 2 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg

Normal Tissue Figure 3 Colon

Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg

Normal Tissue Figure 4 Liver

Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg

Normal Tissue Figure 5 Kidney

Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg

Normal Tissue Figure 7 Placenta

Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg

Normal Tissue Figure 8 Lymph node

Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg

RNA Expression Figure 9 RNA cell line category: Cell line enriched (A-431)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR

❮

❯

Specifications

Allele
DQB1*03:02

Class
Class II

MHC Species
Human

Antigen
EGFR

Antigen Species
Human

Peptide
SRALEEKKGNYVVTHG

Conjugate
PE

Application
FCM

Target

Antigen Introduction
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2

Gene ID
1956

UniProt ID
Q504U8

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for MHC-LC4545. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

Bladder Cancer

Non-small Cell Lung Cancer

Pancreatic Cancer

Hepatocellular Carcinoma

Cushing Syndrome

Related Signaling Pathways

JAK-STAT Signaling Pathway

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

Datasheet - MHC-LC4545.pdf

MSDS

MSDS - MHC-LC4545.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "EGFR"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
TAB-020	Anti-Human EGFR Recombinant Antibody (Panitumumab)	ELISA, IP, FC, FuncS, Neut, IF, ICC	IgG2 - kappa
TAB-278MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-278MZ-F(E))	ELISA, WB	Human Fab
TAB-279MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-279MZ-F(E))	ELISA, WB	Human Fab
TAB-282MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-282MZ-F(E))	ELISA	Human Fab
TAB-283MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-283MZ-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
PSBW-171	Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (PSBW-171)	WB	Mouse scFv
FAMAB-0202-CN-F(E)	Human Anti-EGFR Recombinant Antibody (clone E10); Fab Fragment	ELISA, WB	Human Fab
HPAB-1443LY-F(E)	Human Anti-EGFR Recombinant Antibody (clone P1X); Fab Fragment	ELISA, WB	Human Fab
HPAB-1444LY-F(E)	Human Anti-EGFR Recombinant Antibody (clone P2X); Fab Fragment	ELISA, WB	Human Fab
HPAB-1445LY-F(E)	Human Anti-EGFR Recombinant Antibody (clone P3X); Fab Fragment	ELISA, WB	Human Fab

CAT	Product Name	Application	Type
TAB-0225CL	Human Anti-EGFR Recombinant Antibody (TAB-0225CL)	Block, Inhib, FuncS, Apop, In vivo	Chimeric (Mouse/Human) IgG1
TAB-272MZ	Human Anti-EGFR Recombinant Antibody (TAB-272MZ)	FuncS	Chimeric (mouse/human) IgG
TAB-302MZ	Human Anti-EGFR Recombinant Antibody (TAB-302MZ)	ELISA	Chimeric (mouse/human) IgG1
TAB-308MZ	Human Anti-EGFR Recombinant Antibody (TAB-308MZ)	FuncS	Chimeric antibody (mouse/human)
TAB-272MZ-S(P)	Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-272MZ-S(P))	FuncS	Mouse scFv

CAT	Product Name	Application	Type
TAB-273MZ-F(E)	Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-273MZ-F(E))	FC	Mouse Fab
TAB-275MZ-F(E)	Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-275MZ-F(E))	FC	Mouse Fab
TAB-276MZ-F(E)	Anti-Human EGFR Recombinant Antibody Fab Fragment (LA1)	MTT assay
TAB-277MZ-F(E)	Anti-Human EGFR Recombinant Antibody Fab Fragment (LA22)	MTT assay
TAB-281MZ-F(E)	Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-281MZ-F(E))	WB, IF, IHC	Mouse Fab

CAT	Product Name	Application	Type
TAB-274MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-274MZ-F(E))	FC	Humanized Fab
TAB-297MZ-F(E)	Anti-Human EGFR Recombinant Antibody Fab Fragment (H225)	ELISA, WB	Humanized antibody
TAB-298MZ-F(E)	Anti-Human EGFR Recombinant Antibody Fab Fragment (Hu225)	ELISA, WB	Humanized antibody
TAB-300MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-300MZ-F(E))	ELISA	Humanized Fab
PABX-052	Recombinant Human Anti-EGFR Antibody (PABX-052)	WB, ELISA, FuncS, IB, FC, SPR, Apop	IgG

CAT	Product Name	Application	Type
Gly-055LC	Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated)	ELISA	Chimeric antibody (mouse/human)
Gly-144LC	Recombinant Anti-Human EGFR Antibody (Fc glycosylation)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
Gly-055LC-1	Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
Gly-167LC	Recombinant Anti-Human EGFR Antibody (Non-glycosylated)	ELISA	Human antibody

CAT	Product Name	Application	Type
BRD-0183MZ	Chicken Anti-EGFR Polyclonal IgY	WB	Chicken antibody

CAT	Product Name	Application	Type
MHC-LC773	A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer	FCM

CAT	Product Name	Application	Type
NEUT-722CQ	Rabbit Anti-EGFR Recombinant Antibody (clone CBL1011)	Neut	Rabbit IgG
NEUT-723CQ	Mouse Anti-EGFR Recombinant Antibody (clone CBL931)	WB, IP, IHC, ICC, Neut	Mouse IgG1
NEUT-724CQ	Rabbit Anti-EGFR Recombinant Antibody (NEUT-724CQ)	IF, FC, WB, IP, Neut	Rabbit IgG

CAT	Product Name	Application	Type
MOR-1101	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone DS1101AB)	IHC-P	Rabbit IgG
MOR-4570	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH82DS)	ELISA	Rabbit IgG
MOR-4571	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH83DS)	WB, IF, ICC, FC	Rabbit IgG
MOR-4675	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH189DS)	WB, IF, ICC, FC	Rabbit IgG
MOR-4676	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH190DS)	WB, IF, ICC, FC	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0010-YC-S(P)	Mouse Anti-EGFR Recombinant Antibody (clone L211C); scFv Fragment	ELISA, FC	Mouse scFv
HPAB-0011-YC-S(P)	Human Anti-EGFR Recombinant Antibody (clone Pep 1); scFv Fragment	FC	Human scFv
HPAB-0012-YC-S(P)	Human Anti-EGFR Recombinant Antibody (clone Pep 2); scFv Fragment	FC	Human scFv
HPAB-0013-YC-S(P)	Human Anti-EGFR Recombinant Antibody (clone Pep 3); scFv Fragment	FC	Human scFv
HPAB-0014-YC-S(P)	Human Anti-EGFR Recombinant Antibody (clone Pep 4); scFv Fragment	FC	Human scFv

CAT	Product Name	Application	Type
HPAB-1443LY	Human Anti-EGFR Recombinant Antibody (clone P1X)	ELISA, WB	Human IgG
HPAB-1444LY	Human Anti-EGFR Recombinant Antibody (clone P2X)	ELISA, WB	Human IgG
HPAB-1445LY	Human Anti-EGFR Recombinant Antibody (clone P3X)	ELISA, WB	Human IgG
HPAB-1446LY	Human Anti-EGFR Recombinant Antibody (clone 25E)	ELISA, WB	Human IgG
HPAB-0136-YJ	Human Anti-EGFR Recombinant Antibody (HPAB-0136-YJ)	ELISA, FC, Inhib, FuncS	Human IgG1

CAT	Product Name	Application	Type
AFC-TAB-165	Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-165)	Neut, ELISA, IF, IP, FuncS, FC	ADCC enhanced antibody
AFC-TAB-464CQ	Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-464CQ)	ELISA, IHC, FC, IP, IF, FuncS	ADCC enhanced antibody
AFC-TAB-003	Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-003)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody
AFC-TAB-040	Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-040)	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody
AFC-TAB-119	Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-119)	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody

CAT	Product Name	Application	Type
HPAB-AP881-YC	Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP881-YC)	ELISA, FC, IP, FuncS	Llama VHH
HPAB-AP882-YC	Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP882-YC)	ELISA	Llama VHH
HPAB-AP883-YC	Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP883-YC)	ELISA	Llama VHH
HPAB-AP884-YC	Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP884-YC)	ELISA	Llama VHH
HPAB-AP885-YC	Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP885-YC)	ELISA	Llama VHH

CAT	Product Name	Application	Type
VS-0424-XY84	AbPlus™ Anti-EGFR Magnetic Beads (pSEX81-6)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0924-YC32	Mouse Anti-EGFR Recombinant Antibody (VS-0924-YC32) - Cancer Stem Cell Marker	IHC, WB	Mouse IgG1
VS-0924-YC35	Rabbit Anti-EGFR Antibody (VS-0924-YC35) - Cancer Stem Cell Marker	IHC, WB, IF	Rabbit IgG

CAT	Product Name	Application	Type
VS-1024-XY177	Mouse Anti-NHP EGFR Recombinant Antibody (clone 225)	IF, IP	Mouse IgG1

CAT	Product Name	Application	Type
VS-0125-FY28	Human Anti-EGFR (clone ABT-806) scFv-Fc Chimera	FC, Cyt	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0225-XY102	CytoStream™ Mouse Anti-EGFR Recombinant Antibody (VS-0225-XY102)	FC	Mouse IgG1, kappa

CAT	Product Name	Application
VS-0325-XY735	Anti-EGFR Immunohistochemistry Kit	IHC
VS-0525-XY2183	Anti-Mouse EGFR Immunohistochemistry Kit	IHC
VS-0525-XY2182	Anti-Human EGFR Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0425-YC340	Recombinant Anti-EGFR Vesicular Antibody, EV Displayed (VS-0425-YC340)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-YC65	Recombinant Anti-EGFR (AA 269-278 x AA 526-535) Biparatopic Antibody, Tandem scFv (Clone Pep 2 x Clone Pep 3)	FC	Tandem scFv
VS-0525-YC66	Recombinant Anti-EGFR (AA 582-591 x AA 606-614) Biparatopic Antibody, Tandem scFv (Clone Pep 4 x Clone Pep 1)	FC	Tandem scFv
VS-0525-YC68	Recombinant Anti-EGFR (AA 526-535 x AA 600-605) Biparatopic Antibody, Tandem scFv (Clone Pep 3 x Clone Pep 5)	FC	Tandem scFv
VS-0525-YC213	Recombinant Anti-EGFR (Domain II x Domain III) Biparatopic Antibody, Tandem scFv	ELISA, FC, IF, IHC, IP	Tandem scFv

Specific Inquiry

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 2 Anti-Human EGFR Recombinant Antibody (TAB-020) in ELISA

Anti-Human EGFR Recombinant Antibody (Panitumumab) (CAT# TAB-020)
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

Figure 10 Blockade of PD-1/PD-L1 interaction by anti-PD-1 antibody (Cat# TAB-770) resulted in an increase of IFN-γ production.

Anti-PDCD1 Recombinant Antibody (TAB-770) (CAT# TAB-770)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 4 Anti-CD33 Recombinant Antibody (TAB-756) in SEC-HPLC

Anti-CD33 Recombinant Antibody (TAB-756) (CAT# TAB-756)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 3 Anti-CD40 Antibody (TAB-126CL) in Dot Blot

Human Anti-CD40 Recombinant Antibody (TAB-126CL) (CAT# TAB-126CL)
Application: Block, Cyt, FuncS, Inhib

Figure 1 Recombinant Human Anti-RSV Antibody (PABL-321) in SDS-PAGE

Recombinant Human Anti-RSV Antibody (AM14) (CAT# PABL-321)
Application: WB, ELISA, Neut, FuncS

Figure 3 Anti-CA9 Antibody in Dot Blot.

Mouse Anti-CA9 Recombinant Antibody (clone M75) (CAT# PABZ-017)
Application: WB, FuncS

Figure 2 Anti-Recombinant BTN3A1 Antibody (PABL-415) in ELISA

Mouse Anti-BTN3A1 Recombinant Antibody (clone 103.2) (CAT# PABL-415)
Application: FuncS

Figure 6 Anti-LAM Recombinant Antibody (PABW-158, lot#CB2206LX02P6) in SEC-HPLC

Mouse Anti-LAM Recombinant Antibody (clone CS-35) (CAT# PABW-158)
Application: ELISA, IF, FC

Figure 2 Human Anti-CD3 Recombinant Antibody (TAB-0416CL-S(P)) in WB

Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P)) (CAT# TAB-0416CL-S(P))
Application: IB, ELISA, FC, FuncS

Figure 2 Anti-CD3 Recombinant Antibody (TAB-0416CL-F(E)) in HPLC

Mouse Anti-CD3 Recombinant Antibody Fab Fragment (TAB-0416CL-F(E)) (CAT# TAB-0416CL-F(E))
Application: IB, ELISA, FC, FuncS

Figure 2 Anti-CLDN4 Antibody (TAB-501LC) in HPLC

Anti-Human CLDN4 Recombinant Antibody (KM3900) (CAT# TAB-501LC)
Application: WB, IP, FC

Figure 2 Anti-Human TEM7R Recombinant Antibody (TAB-577CT) in HPLC

Human Anti-PLXDC2 Recombinant Antibody (TAB-577CT) (CAT# TAB-577CT)
Application: ELISA, FC, IHC, IF

Figure 5 Human Anti-SLC34A2 Recombinant Antibody (TAB-468MZ) in DB

Human Anti-SLC34A2 Recombinant Antibody (TAB-468MZ) (CAT# TAB-468MZ)
Application: FC, Inhib

Figure 4 Anti-Human SNCA Antibody (TAB-0750CLV) in HPLC

Mouse Anti-SNCA Recombinant Antibody (TAB-0750CLV) (CAT# TAB-0750CLV)
Application: ELISA

Figure 2 Human Anti-RSV F Recombinant Antibody (MRO-878LC) in ELISA

Human Anti-RSV F Recombinant Antibody (MRO-878LC) (CAT# MRO-878LC)
Application: ELISA, Neut

Figure 2 Recombinant Human Anti-EGFR Antibody (PABX-052) in HPLC

Recombinant Human Anti-EGFR Antibody (PABX-052) (CAT# PABX-052)
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop

Figure 3 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-S(P)) in ELISA

Rat Anti-IL18 Recombinant Antibody (clone 2C10); scFv Fragment (CAT# HPAB-0067-YC-S(P))
Application: Neut

Figure 3 Anti-C5 Recombinant Antibody (PABC-462) in DB

Human Anti-C5 Recombinant Antibody (PABC-462) (CAT# PABC-462)
Application: WB, HA, ELISA, FC, Neut

Figure 1 Mouse Anti-RNA Recombinant Antibody (PABC-495) in SDS-PAGE

Mouse Anti-RNA Recombinant Antibody (PABC-495) (CAT# PABC-495)
Application: ELISA

Figure 5 Anti-Human CDH17 Recombinant Antibody (HPAB-2061LY) in ELISA

Human Anti-CDH17 Recombinant Antibody (clone D2101) (CAT# HPAB-2061LY)
Application: ELISA

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.