Loading...
Custom Services order now ship next day

EIF4A1

EIF4A1 (Eukaryotic Translation Initiation Factor 4A1) is a Protein Coding gene. Among its related pathways are Translation Translation regulation by Alpha-1 adrenergic receptors and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is EIF4A2.
Protein class

Enzymes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Basal respiratory cells, Basal keratinocytes, Langerhans cells, Suprabasal keratinocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with PAIP1, EIF4E and UPF2. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. May interact with NOM1. Interacts with PDCD4; this interferes with the interaction between EIF4A and EIF4G. Interacts with RBM4. Interacts with DDX3X in an RNA-independent manner (PubMed:18596238). (Microbial infection) Interacts with human cytomegalovirus/HHV-5 protein UL69.

Molecular function

Helicase, Hydrolase, Initiation factor, RNA-binding

More Types Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

For Research Use Only. Not For Clinical Use.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare