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KRT14
Loading...Anti-KRT14 Products
- AbPlus™ Anti-KRT14 Magnetic Beads (VS-0724-YC1380) (VS-0724-YC1380)
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- Target: KRT14
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
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- AbPlus™ Anti-Krt14 Magnetic Beads (VS-0724-YC1431) (VS-0724-YC1431)
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- Target: Krt14
- Target Species: Mouse
- Application: IP, Protein Purification
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- Chicken Anti-Keratin 14 Polyclonal IgY (BRD-1120MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: IHC
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- Anti-KRT14 Immunohistochemistry Kit (VS-0325-XY1209)
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- Species Reactivity: Human, Mouse, Rat
- Target: KRT14
- Application: IHC
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- Anti-Mouse KRT14 Immunohistochemistry Kit (VS-0525-XY3843)
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- Species Reactivity: Human, Mouse, Rat
- Target: KRT14
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Basal keratinocytes, Suprabasal keratinocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, U-2197)
Interaction
Heterotetramer of two type I and two type II keratins. disulfide-linked keratin-14 associates with keratin-5. Interacts with TRADD and with keratin filaments. Associates with other type I keratins. Interacts with EPPK1 (By similarity). Interacts with KLHL24 (PubMed:27798626).
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