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LTF

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For Research Use Only. Not For Clinical Use.


Background

LTF is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. LTF is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. LTF demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides.
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