PDCD1
This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Species Reactivity: Human
Type: Human IgG4 kappa
Application: WB, ELISA, FuncS
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: ELISA, FC, ICC, IF, IHC
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Species Reactivity: Human
Type: Human Fab
Application: WB, ELISA, FuncS
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Species Reactivity: Human
Type: Human scFv
Application: WB, ELISA, FuncS
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Species Reactivity: Human
Application: FC
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Species Reactivity: Mouse
Type: IgG2a
Application: BL, FC
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Derivation: Phage display library screening
Species Reactivity: Human
Type: IgG
Application: IHC
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Species Reactivity: Mouse
Type: IgG
Application: BL, WB
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Species Reactivity: Mouse
Type: IgG2a
Application: BL, WB
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Species Reactivity: Mouse
Type: IgG2b
Application: BL
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Species Reactivity: Mouse
Type: IgG2
Application: BL, FC
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Species Reactivity: Human
Type: IgG2
Application: Neut, WB
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Species Reactivity: Human
Type: IgG1
Application: BL, WB
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Species Reactivity: Human
Type: IgG1, κ
Application: Neut
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Species Reactivity: Human
Type: IgG2
Application: Neut, WB
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Derivation: Human
Species Reactivity: Human
Type: IgG4 - kappa
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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Species Reactivity: Human
Type: ADCC enhanced antibody
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Derivation: Humanized (from mouse)
Species Reactivity: Human
Type: IgG1 - kappa
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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Derivation: Humanized (from mouse)
Species Reactivity: Human
Type: IgG4, κ
Application: Inhib, Agonist
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Species Reactivity: Human
Type: Mouse IgG
Application: ELISA, Inhib
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For Research Use Only. Not For Clinical Use.