Anti-Human PDCD1 Recombinant Antibody scFv Fragment (949gH1a) (CAT#: TAB-0977CL-S(P))
This antibody which binds to human PD-1 is capable of inducing agonistic signaling through PD-1, leading to inhibition of human CD4+ T cell responses.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg
(Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Species Reactivity
- Cynomolgus and rhesus
- Clone
- 949gH1a
- Applications
- FC
Target
- Alternative Names
- PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2
- Gene ID
- 5133
- UniProt ID
- Q15116
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
Chimeric Antibody
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Blocking Antibody
Neutralizing Antibody
Rabbit Monoclonal Antibody
Recombinant Antibody
Fab Fragment Antibody
scFv Fragment Antibody
ADCC Enhanced Antibody
IgM Antibody
Single-domain Antibody
Agonistic Antibody
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0966CL | Human Anti-PDCD1 Recombinant Antibody (TAB-0966CL) | ELISA | Humanized antibody |
| TAB-0966CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0966CL-S(P)) | ELISA | Human scFv |
| TAB-0975CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0975CL-S(P)) | ELISA | Human scFv |
| TAB-0977CL-F(E) | Anti-Human PDCD1 Recombinant Antibody Fab Fragment (949gH1a) | FC | Humanized antibody |
| TAB-012ML | Anti-Human PDCD1 Recombinant Antibody (Camrelizumab) | ELISA, IHC, FC, IP, IF, BL | IgG4, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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