Rabbit Anti-PDE1B Recombinant Antibody (clone R03-6F9)
CAT#: VS3-FY1819
This R03-6F9 recombinant monoclonal antibody has the ability to specifically bind to human PDE1B. It cross-reacts with mouse, rat. This PDE1B antibody is guaranteed for western blot analysis of PDE1B in rat brain lysates.
Gene Expression
Tested Data
Normal Tissue
Figure 1 High expression in caudate nucleus
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
Normal Tissue
Figure 2 Low expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
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WB
Figure 1 Anti-PDE1B Antibody (VS3-FY1819) in WB.
The PDE1B expression in rat Brain lysates were detected using the anti-PDE1B by western blot assay.
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Specifications
- Immunogen
- Recombinant human PDE1B protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat PDE1B
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R03-6F9
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 61 kDa, while the observed molecular weight stands at 61 kDa.
- Related Disease
- Impotence
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Phosphodiesterase 1B; Phosphodiesterase 1B, Calmodulin-Dependent; 3 KDa Cam-PDE; EC 3.1.4.17; Cam-PDE 1B; PDES1B; PDE1B1; Presumed 63kDa Form Of The Type 1 Cyclic Nucleotide Phosphodiesterase Family Known As PDE1B
- Gene ID
- 5153
- UniProt ID
- Q01064
- Sequence Similarities
- Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q01064)
Modification sites at neXtProt (NX_Q01064)
- Protein Refseq
- XP_016874921.1; XP_016874922.1; XP_047284926.1; XP_054228193.1; XP_054228194.1
- Function
- Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
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Related Signaling Pathways
cAMP Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "PDE1B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2628 | Hi-Affi™ Recombinant Rabbit Anti-PDE1B Monoclonal Antibody (DS2628AB) | WB, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1224 | Mouse Anti-PDE1B Recombinant Antibody (clone 5C4A3) | IHC, FC | Mouse IgG1 |
| VS3-XY1226 | Mouse Anti-PDE1B Recombinant Antibody (clone 5A11) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY1227 | Mouse Anti-PDE1B Recombinant Antibody (clone 5G9) | ELISA, WB, FC, IHC | Mouse IgG1 |
| VS3-XY1228 | Mouse Anti-PDE1B Recombinant Antibody (clone 5H6D4) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY1229 | Mouse Anti-PDE1B Recombinant Antibody (clone 8F11) | ELISA, WB, FC, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY371 | Mouse Anti-NHP PDE1B Recombinant Antibody (clone OTI6B9) | WB, ICC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5265 | Anti-PDE1B Immunohistochemistry Kit | IHC |
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