Rabbit Anti-PDX1 Recombinant Antibody (VS13-YC891) (CAT#: VS13-YC891)
The Rabbit Anti-PDX1 Recombinant Antibody is specific for human PDX1. PDX1 encodes a transcription activator of genes like insulin, crucial for pancreatic development and glucose regulation, with defects causing pancreatic agenesis and diabetes, displaying spliced transcripts. The anti-PDX1 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry-paraffin (1/100-1/800), Immunocytochemistry (1/50-1/200), Immunofluorescence (1/50-1/200).
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/1645_D3_14_cr57beb44007e74_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/1645_D3_14_cr57beb44007e74_selected.jpg
Figure 2 High expression in duodenum
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/139685_A_8_2_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/139685_A_8_2_val_selected.jpg
Figure 3 Low expression in prostate
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/139685_A_3_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59146/139685_A_3_5_val_selected.jpg
Figure 4 Colon
(Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes -)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25873/54802_A_9_3.jpg
(Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes -)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25873/54802_A_9_3.jpg
Figure 5 Pancreas
(Exocrine glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25873/54802_A_1_3.jpg
(Exocrine glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25873/54802_A_1_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HEK93, HeLa, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139515-PDX1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139515-PDX1
Specifications
- Immunogen
- Recombinant human PDX1, aa 234-283.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PDX1
- Species Reactivity
- Human
- Applications
- WB, IHC-P, ICC, IF
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry-paraffin (IHC-P): 1/100-1/800
Immunocytochemistry (ICC): 1/50-1/200
Immunofluorescence (IF): 1/50-1/200
Target
- Alternative Names
- Pancreatic And Duodenal Homeobox 1; Insulin Promoter Factor 1, Homeodomain Transcription Factor; Somatostatin-Transactivating Factor 1; Somatostatin Transcription Factor 1; Insulin Upstream Factor 1; Islet/Duodenum Homeobox-1; Glucose-Sensitive Factor; STF-1; IDX-1; IPF-1; IUF-1;
- Gene ID
- 3651
- UniProt ID
- P52945
- Long Name
- Pancreatic And Duodenal Homeobox 1
- Cellular Localization
- Nucleus; Cytosol
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
Type I Diabetes Mellitus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3868z | Mouse Anti-PDX1 Recombinant Antibody (clone 30D12) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MRO-1202-CN | Recombinant Rabbit Anti-PDX1 Monoclonal Antibody (JM62-45) | WB, IHC, IF | Rabbit IgG |
| VS3-QX864 | Mouse Anti-PDX1 Recombinant Antibody (clone 5A5) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-WK601 | Rabbit Anti-PDX1 Recombinant Antibody (clone JM62-45) | WB, ELISA | Rabbit IgG |
| VS3-XY1236 | Mouse Anti-PDX1 Recombinant Antibody (clone 2G12) | ELISA, WB, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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