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PPP4C
Loading...Anti-PPP4C Products
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- Species Reactivity: Human, Mouse, Rat, Bovine, Dog, Zebrafish
- Type: Mouse IgG
- Application: WB, IHC, IF
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- Species Reactivity: Human, Dog, Mouse, Bovine, Rat
- Type: Mouse IgG2a
- Application: ELISA, WB, IHC, ICC
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- AbPlus™ Anti-PPP4C Magnetic Beads (VS-0724-YC1005) (VS-0724-YC1005)
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- Target: PPP4C
- Target Species: Human
- Application: IP, Protein Purification
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- Mouse Anti-PPP4C Recombinant Antibody (VS7-0425-WR670) (VS7-0425-WR670)
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- Species Reactivity: Human, Mouse, Rat, Bovine, Dog, Zebrafish
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC
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- Anti-PPP4C Immunohistochemistry Kit (VS-0325-XY1728)
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- Species Reactivity: Human, Mouse, Rat
- Target: PPP4C
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Enables protein serine/threonine phosphatase activity. Involved in regulation of double-strand break repair via homologous recombination. Located in cytosol; nucleoplasm; and plasma membrane. Part of chromatin and protein phosphatase 4 complex. [provided by Alliance of Genome Resources, Mar 2025]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits (PubMed:12668731, 18715871, 16085932, 18614045). Component of the PP4 complexes PPP4C-PPP4R1, PPP4C-PPP4R2, PPP4C-PPP4R2-PPP4R3A, PPP4C-PPP4R2-PPP4R3B and PPP4C-PPP4R4 (PubMed:12668731, 18715871, 16085932, 18614045). The PPP4C-PPP4R2 complex appears to be a tetramer composed of 2 molecules of PPP4C and 2 molecules of PPP4R2 (PubMed:12668731). Interacts with REL, NFKB1/p50 and RELA (PubMed:1336397). Interacts with SMN1 and GEMIN4 (PubMed:12668731). Interacts with IRS4 (phosphorylated) (PubMed:15331607). Interacts with SMEK1/PPP4R3A; the interaction requires PP4R2 (PubMed:16085932). Interacts with HDAC3 (PubMed:15805470).
Molecular function
Hydrolase, Protein phosphatase
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