Rabbit Anti-SUMO1 Recombinant Antibody (VS3-CJ1101)
CAT#: VS3-CJ1101
This product is a rabbit antibody that recognizes human, mouse, and rat SUMO1.
Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat SUMO1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC, IP, FC, ChIP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry, Chromatin Immunoprecipitation.
Target
- Alternative Names
- DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3
- Gene ID
- 7341
- UniProt ID
- P63165
- Sequence Similarities
- Belongs to the ubiquitin family. SUMO subfamily.
- Cellular Localization
- Cell membrane, Cytoplasm, Membrane, Nucleus
- Post Translation Modifications
- Cleavage of precursor form by SENP1 or SENP2 is necessary for function.
Polymeric SUMO1 chains undergo polyubiquitination by RNF4.
- Protein Refseq
- NP_001005781.1; NP_001005782.1; NP_003343.1
- Function
- Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed:19223394).
Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed:24651376).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SUMO1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0267MC | Recombinant Anti-SUMO-1 Antibody | WB, IP, IF, IHC(P), ELISA | |
| MOB-0413ZL | Goat anti-Human SUMO-1 Antibody | WB, IP, IF, ELISA | |
| MOB-603NL | Recombinant Anti-Human SUMO1 Antibody | WB, ELISA | |
| MOB-1981CT | Recombinant Mouse anti-Human SUMO1 Monoclonal antibody (opof) | ICC, IF, IP, WB | |
| MRO-1452-CN | Recombinant Rabbit Anti-SUMO1 Monoclonal Antibody (CBACN-538) | WB, IF, IHC, IP, FC, ChIP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3460 | Hi-Affi™ Recombinant Rabbit Anti-SUMO1 Monoclonal Antibody (DS3460AB) | WB, IHC-P, ICC, IF, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1166 | AbPlus™ Anti-SUMO1 Magnetic Beads (VS-0724-YC1166) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY496 | Rabbit Anti-NHP SUMO1 Recombinant Antibody (VS-1024-XY496) | WB, IHC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1130 | CytoStream™ Rabbit Anti-SUMO1 Recombinant Antibody (VS13-YC1130) | WB, ICC, IF, IHC-P, IP, FC, ChIP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2228 | Anti-SUMO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7021 | Anti-Mouse SUMO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7020 | Anti-Human SUMO1 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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