APC-A*24:02/Human GPC3 (EYILSLEEL) MHC Tetramer (CAT#: MHC-LC043)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of GPC3-derived peptide of EYILSLEEL sequence covering 298-306 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • Antigen
  • GPC3
  • Antigen Species
  • Human
  • Peptide
  • EYILSLEEL
  • Range
  • 298-306
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • GPC3; glypican 3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2

Downloads

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Immunotoxin

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Chimeric Antibody

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Rabbit Monoclonal Antibody

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MOR-1486 Hi-Affi™ Rabbit Anti-GPC3 Recombinant Antibody (clone DS1486AB) IHC-P Rabbit IgG

Recombinant Antibody

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HPAB-0556-CN Human Anti-GPC3 Recombinant Antibody (HPAB-0556-CN) ELISA, WB Chimeric (mouse/human) IgG1, κ
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HPAB-0558-CN Mouse Anti-GPC3 Recombinant Antibody (HPAB-0558-CN) ELISA, WB Mouse IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H14 Afuco™ Anti-GPC3 ADCC Recombinant Antibody (Codrituzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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