GPC3

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Anti-GPC3 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs offers a diverse range of top-notch anti-GPC3 recombinant antibodies, meticulously engineered to deliver superior performance. Our cutting-edge platform ensures exceptional specificity, stability, and efficacy, making these antibodies invaluable assets for researchers and developers in the field of targeted cancer therapy.

GPC3: An Attractive Target for Cancer Therapy

Glypican-3 (GPC3) is a protein primarily expressed during embryonic development and in hepatocellular carcinoma (HCC) tumor cells. Its unique expression pattern, absent in most normal adult tissues and liver diseases like fatty liver, cirrhosis, hepatitis, or liver damage, makes GPC3 an ideal target for both diagnosing and treating HCC. This specificity allows for the development of diagnostic tools and therapeutic strategies that selectively target HCC cells, minimizing harm to healthy tissues.

Alternative Names

Glypican-3; Glypican 3; DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1.

Background

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Anti-GPC3 rAb Products

Creative Biolabs provides a collection of recombinant anti-GPC3 antibodies that have been rigorously developed to display high specificity and affinity. These antibodies are available in a variety of forms and are designed for a wide range of studies and therapeutic applications, spanning basic research to therapeutic development. Based on our robust platform, we deliver cutting-edge tools to advance the research of immunology, cancer biology, and related topics, as well as facilitate therapeutics development.

Table 1. Featured anti-GPC3 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs provides a complete spectrum of anti-GPC3 recombinant antibodies that have undergone rigorous quality testing. Our cutting-edge facilities and expert scientists precisely develop each antibody to target GPC3 with pinpoint accuracy. Through rigorous testing and validation, we ensure that these antibodies exhibit superior specificity, strong binding affinity, and other optical properties in a wide range of research applications.

Customer Reviews

Excellent

X Zh***g
Mouse Anti-GPC3 Recombinant Antibody (clone GC33) (HPAB-0561-CN)

Creative Biolabs' anti-GPC3 recombinant antibody performed admirably in our ELISA testing. The antibody demonstrated outstanding specificity and sensitivity, allowing us to quantify GPC3 levels in an array of biological samples precisely. This antibody's constant performance and ease of usage greatly improved our research productivity and data quality.

20/Feb/2022

Excellent

T* Sh**h
Human Anti-GPC3 Recombinant Antibody (clone hGC33) (HPAB-0563-CN)

We were impressed with the quality and performance of Creative Biolabs' anti-GPC3 recombinant antibody. When used in our ELISA assays, it yielded robust and reproducible results. The antibody's strong binding affinity and high specificity enabled us to detect and quantify GPC3, even at low concentrations confidently. We highly recommend this product for researchers working on HCC research.

6/Aug/2023

Excellent

Yv***e
Human Anti-GPC3 Recombinant Antibody (HPAB-0692-WJ) (HPAB-0692-WJ)

We have been highly satisfied with Creative Biolabs' anti-GPC3 recombinant antibody for both Western Blot and Flow cytometry applications. The antibody consistently delivers strong, specific bands in WB analysis, enabling accurate protein detection. In flow cytometry, it provides clear and distinct staining of GPC3-positive cells, facilitating precise cell population analysis. The versatility and reliability of this antibody have been invaluable in our research efforts.

9/Nov/2023

rAb Production

Creative Biolabs provides a consistent supply of superior anti-GPC3 antibodies that are produced using cutting-edge genetic technologies.

Featured Anti-GPC3 Recombinant Antibody Production Platforms
Fig.7 Milligram-scale anti-GPC3 recombinant antibody production.

Fig.8 Gram-scale anti-GPC3 recombinant antibody production.

rAb Modalities

Creative Biolabs provides a wide range of high-quality anti-GPC3 recombinant antibodies with diverse formats to meet global researchers’ various demands.

Fig.9 Full-length anti-GPC3 recombinant antibody production and modalities.

GPC3-Targeted Drug Information

Table 2. Public drug targeting GPC3.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

For more information or to inquire about our anti-GPC3 recombinant antibody products, please contact us at any time.